Rostami-Afshari B, Elremaly W, Franco A, Elbakry M, Akoume MY, Boufaied I, Moezzi A, Leveau C, Rompré P, Godbout C, Mella O, Fluge Ø, Moreau A. SMPDL3B a novel biomarker and therapeutic target in myalgic encephalomyelitis. J Transl Med. 2025 Jul 7;23(1):748.
Metayer I, Forest-Nault C, Guimond J, Joubert S, Henry O, Durocher Y, De Crescenzo G, Gaudreault J. A Surface Plasmon Resonance-Based Integrated Assay for Quantification and Glycosylation Characterization of Monoclonal Antibodies in Crude Heterogeneous Samples. Biotechnol Bioeng. 2025 Jul 5. doi: 10.1002/bit.70016.
Ahmed O, Masclef L, Iannantuono N, Gagnon J, Gushul-Leclaire M, Boulay K, Estavoyer B, Echbicheb M, Ali Boubacar K, Poy M, Boubekeur A, Menggad S, Schcolnik-Cabrera A, Balsalobre A, Bonneil E, Thibault P, Hulea L, Mallette FA, Drouin J, Tanaka Y, Affar EB. O-GlcNAcylation of FOXK1 co-opts BAP1 to orchestrate the E2F pathway and promotes oncogenesis. Nat Commun. 2025 Jul 1;16(1):5959.
Rodriguez MM, Chatterjee D, Guerry J, Patenaude AM, Cohen CCH, Bois T, Larouche A, Ferreira SR, Bertomeu T, Chatr-Aryamontri A, Zhang L, Mader S, Nislow C, St-Jean G, Guindon Y, Zahn A, Di Noia JM. CDADC1 is a vertebrate-specific dCTP deaminase that metabolizes gemcitabine and decitabine to prevent cellular toxicity. Proc Natl Acad Sci U S A. 2025 Jun 17;122(24):e2424409122.
Morales-Pastor A, Miljuš T, Dieguez-Eceolaza M, Stępniewski TM, Ledesma-Martin V, Heydenreich FM, Flock T, Plouffe B, Le Gouill C, Duchaine J, Sykes DA, Nicholson C, Koers EJ, Guba W, Rufer AC, Grether U, Bouvier M, Veprintsev DB, Selent J. Multiple intramolecular triggers converge to preferential G protein coupling in the CB2R. Nat Commun. 2025 Jun 11;16(1):5265.
Reyes SJ, Voyer R, Durocher Y, Henry O, Pham PL. A recurrent neural network for soft sensor development using CHO stable pools in fed-batch process for SARS-CoV-2 spike protein production as a vaccine antigen. Biotechnol Prog. 2025 Jun 2:e70046. doi: 10.1002/btpr.70046.
Bourassa FXP, François P, Reddy G, Vergassola M. Manifold learning for olfactory habituation to strongly fluctuating backgrounds. bioRxiv [Preprint]. 2025 May 30:2025.05.26.656161.
Mignaqui AC, Ferella A, Sánchez C, Stuible M, Scian R, Filippi J, Cardillo SB, Durocher Y, Wigdorovitz A. Optimized Production of Virus-like Particles in a High-CHO-Cell-Density Transient Gene Expression System for Foot-and-Mouth Disease Vaccine Development. Vaccines (Basel). 2025 May 29;13(6):581.
Higazy-Mreih S, Avital-Shacham M, LeGouill C, Bouvier M, Kosloff M. Gαs-specific structural elements attenuate interactions with regulator of G protein signaling (RGS) proteins. FEBS J. 2025 May 28. doi: 10.1111/febs.70149.
Gemeinhardt TM, Regy RM, Phan TM, Pal N, Sharma J, Senkovich O, Mendiola AJ, Ledterman HJ, Henrickson A, Lopes D, Kapoor U, Bihani A, Sihou D, Kim YC, Jeruzalmi D, Demeler B, Kim CA, Mittal J, Francis NJ. A disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization. Mol Cell. 2025 May 23:S1097-2765(25)00413-7.
Frigon L, Pascal JM. Crystal structure and mutagenesis of a nucleic acid-binding BRCT domain in human PARP4. J Biol Chem. 2025 May 22:110277. doi: 10.1016/j.jbc.2025.110277.
Apavaloaei A, Zhao Q, Hesnard L, Cahuzac M, Durette C, Larouche JD, Hardy MP, Vincent K, Brochu S, Laverdure JP, Lanoix J, Courcelles M, Gendron P, Lajoie M, Ruiz Cuevas MV, Kina E, Perrault J, Humeau J, Ehx G, Lemieux S, Watson IR, Speiser DE, Bassani-Sternberg M, Thibault P, Perreault C. Tumor antigens preferentially derive from unmutated genomic sequences in melanoma and non-small cell lung cancer. Nat Cancer. 2025 May 22. doi: 10.1038/s43018-025-00979-2.
Lopes-Paciencia S, Ferbeyre G. Increased chromatin accessibility underpins senescence. FEBS J. 2025 May 19. doi: 10.1111/febs.70136.
Harris J, Mayran A, Gouhier A, Gauthier Y, Sleiman NH, Merabet S, Dukatz M, Bashtrykov P, Jeltsch A, Djambazian H, Chen SH, Balsalobre A, Drouin J. Dual DNA demethylation mechanisms implement epigenetic memory driven by the pioneer factor PAX7. Sci Adv. 2025 May 16;11(20):eadu6632.
Kondo T, Bourassa FXP, Achar S, DuSold J, Céspedes PF, Ando M, Dwivedi A, Moraly J, Chien C, Majdoul S, Kenet AL, Wahlsten M, Kvalvaag A, Jenkins E, Kim SP, Ade CM, Yu Z, Gaud G, Davila M, Love P, Yang JC, Dustin ML, Altan-Bonnet G, François P, Taylor N. Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity. Cell. 2025 May 1;188(9):2372-2389.e35.
Padilla JA, Barutcu S, Boulais J, da Silva JC, Chen Y, Syed E, Kwon E, Lécuyer E. Inhibition of acid or neutral sphingomyelinases differentially impacts RNA and protein cargo sorting to extracellular vesicles. iScience. 2025 Apr 15;28(5):112440.
Métois A, Bordeleau ME, Theret L, Hajmirza A, Moujaber O, Spinella JF, Chagraoui J, Mayotte N, Boivin I, Audemard É, Aubert L, Lisi V, Khakipoor B, Farah A, Bonneil É, Robert A, Lippens J, Moraitis A, Béliveau F, Feghaly A, Boucher G, Marcotte R, Gendron P, Thibault P, Lemieux S, Richard-Carpentier G, Lavallée VP, Hébert J, Roux PP, Sauvageau G. IL1RAP is an immunotherapeutic target for normal karyotype triple-mutated acute myeloid leukemia. Biomark Res. 2025 Apr 14;13(1):61.
Renner TM, Stuible M, Rossotti MA, Rohani N, Cepero-Donates Y, Sauvageau J, Deschatelets L, Dudani R, Harrison BA, Baardsnes J, Koyuturk I, St Michael F, Hill JJ, Hemraz UD, Lenferink AEG, Tanha J, Fernandes B, Roldao A, McCluskie MJ, Akache B, Durocher Y. Modifying the glycosylation profile of SARS-CoV-2 spike-based subunit vaccines alters focusing of the humoral immune response in a mouse model. Commun Med (Lond). 2025 Apr 11;5(1):111.
Kaya F, Bewicke-Copley F, Miettinen JJ, Casado P, Leddy E, Deniz Ö, Lavallée VP, Philippe C, Zheng J, Grebien F, Khan N, Krizsán S, Saad J, Nolin-Lapalme A, Hébert J, Lemieux S, Audemard E, Matthews J, Grantham M, Di Bella D, Wennerberg K, Parsons A, Gribben J, Cavenagh JD, Freeman SD, Bödör C, Sauvageau G, Wang J, Llamas-Sillero P, Cazier JB, Taussig DC, Bonnet D, Cutillas PR, Heckman CA, Fitzgibbon J, Rouault-Pierre K, Rio-Machin A. DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes. Leukemia. 2025 Apr 9. doi: 10.1038/s41375-025-02593-8.
Lemire L, Reyes SJ, Durocher Y, Voyer R, Henry O, Pham PL. N-1 semi-continuous transient perfusion in shake flask for ultra-high density seeding of CHO cell cultures in benchtop bioreactors. Biotechnol Prog. 2025 Apr 3:e70029.
Thimmappa BC, Sarrasin M, Lang BF, Burger G. The draft genome sequence of Diaporthe vaccinii, isolated from diseased cranberries. Microbiol Resour Announc. 2025 Apr 2:e0046624.
Carroll M, Fox HB, Tran A, Chellappan G, Rojas LV, Karengil G, Karandish F, Langston JW, Fall BM, Whalen MM, McCluskie MJ, Durocher Y, Datta A, Kapre SV, Olave IA. SARS-CoV-2 conjugate vaccine elicits robust immune responses that can protect against evolving variants. Vaccine. 2025 Mar 6;54:126988.
Francis NJ. A chromatin mesh model for compaction of chromatin by PRC1 in condensates. Nat Struct Mol Biol. 2025 Mar;32(3):411-413.
Ferbeyre G. A one-two punch against cancer: combining CDK4 inhibitors with lysosomotropic agents. EMBO J. 2025 Feb 24. doi: 10.1038/s44318-025-00396-2.
Li J, Wang X, Jordana L, Bonneil É, Ginestet V, Ahmed M, Bourouh M, Pascariu CM, Schmeing TM, Thibault P, Archambault V. Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis. Elife. 2025 Feb 18;13:RP104233.
Teixeira LB, Blouin MJ, Le Gouill C, Picard LP, Costa-Neto CM, Bouvier M, Parreiras-E-Silva LT. Sustained Gαs signaling mediated by vasopressin type 2 receptors is ligand dependent but endocytosis and β-arrestin independent. Sci Signal. 2025 Feb 18;18(874):eadf6206.
Khatami N, Caraus I, Rahaman M, Nepotchatykh E, Elbakry M, Elremaly W, Franco A, Beauséjour M, Laberge AM, Parent S, Labelle H, Aubin CÉ, Lachaine J, Moreau A. Genome-wide profiling of circulating microRNAs in adolescent idiopathic scoliosis and their relation to spinal deformity severity, and disease pathophysiology. Sci Rep. 2025 Feb 12;15(1):5305.
Panichnantakul P, Oeffinger M. Protocol for the purification and analysis of nuclear UFMylated proteins. STAR Protoc. 2025 Feb 10;6(1):103634.
Reyes SJ, Pham PL, Durocher Y, Henry O. CHO stable pool fed-batch process development of SARS-CoV-2 spike protein production: Impact of aeration conditions and feeding strategies. Biotechnol Prog. 2025 Jan-Feb;41(1):e3507.
Elbakry M, Khatami N, Akoume MY, Julien C, Bouhanik S, Franco A, Caraus I, Elremaly W, Moreau A. Loss of Tyrosine Phosphatase Mu Promotes Scoliosis Progression Through Osteopontin-α5β1 Integrin Signaling and PIPK1γ90 Activity. Int J Mol Sci. 2025 Jan 26;26(3):1042.
Smith-Pillet ES, Billur R, Langelier MF, Talele TT, Pascal JM, Black BE. A PARP2 active site helix melts to permit DNA damage-induced enzymatic activation. Mol Cell. 2025 Jan 24:S1097-2765(25)00004-8.
Nieman LK, Castinetti F, Newell-Price J, Valassi E, Drouin J, Takahashi Y, Lacroix A. Cushing syndrome. Nat Rev Dis Primers. 2025 Jan 23;11(1):4.
Reyes SJ, Lemire L, Durocher Y, Voyer R, Henry O, Pham PL. Investigating the metabolic load of monoclonal antibody production conveyed to an inducible CHO cell line using a Transfer-Rate Online Monitoring system. J Biotechnol. 2025 Jan 17:S0168-1656(25)00008-2.
Cheng SJ, Gafaar T, Kuttiyatveetil JRA, Sverzhinsky A, Chen C, Xu M, Lilley A, Pascal JM, Leung AKL. Regulation of stress granule maturation and dynamics by poly(ADP-ribose) interaction with PARP13. Nat Commun. 2025 Jan 13;16(1):621.
Hashimoto-Roth E, Forget D, Gaspar VP, Bennett SAL, Gauthier MS, Coulombe B, Lavallée-Adam M. MAGPIE: A Machine Learning Approach to Decipher Protein-Protein Interactions in Human Plasma. J Proteome Res. 2025 Jan 7.
Bonneil É, Larouche M, Emond-Fraser V, Kubiniok P, Pascariu CM, Thibault P, Archambault V. Studying Mitotic Phosphorylation in Drosophila. Methods Mol Biol. 2025;2874:167-182.
Padilla JA, Barutcu S, Deschamps-Francoeur G, Lécuyer E. Exploring Extracellular Vesicle Transcriptomic Diversity Through Long-Read Nanopore Sequencing. Methods Mol Biol. 2025;2880:227-241.
