Gaud G, Achar S, Bourassa FXP, Davies J, Hatzihristidis T, Choi S, Kondo T, Gossa S, Lee J, Juneau P, Taylor N, Hinrichs CS, McGavern DB, François P, Altan-Bonnet G, Love PE. CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides. Nat Immunol. 2023 Dec;24(12):2121-2134.
Lefkowitz RJ, Rockman HA, Shim PJ, Liu S, Ahn S, Pani B, Rajagopal S, Shenoy SK, Bouvier M, Benovic JL, Liggett SB, Ruffolo RR, Bristow MR, Packer M. How carvedilol does not activate β2-adrenoceptors. Nat Commun. 2023 Nov 30;14(1):7866.
Frigon L, Pascal JM. Structural and biochemical analysis of the PARP1-homology region of PARP4/vault PARP. Nucleic Acids Res. 2023 Nov 16:gkad1064.
Sachan V, Le Dévéhat M, Roubtsova A, Essalmani R, Laurendeau JF, Garçon D, Susan-Resiga D, Duval S, Mikaeeli S, Hamelin J, Evagelidis A, Chong M, Paré G, Chernetsova E, Gao ZH, Robillard I, Ruiz M, Trinh VQ, Estall JL, Faraj M, Austin RC, Sauvageau M, Prat A, Kiss RS, Seidah NG. PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease. Metabolism. 2023 Nov 13:155736.
Bottero D, Rudi E, Martin Aispuro P, Zurita E, Gaillard E, Gonzalez Lopez Ledesma MM, Malito J, Stuible M, Ambrosis N, Durocher Y, Gamarnik AV, Wigdorovitz A, Hozbor D. Heterologous booster with a novel formulation containing glycosylated trimeric S protein is effective against Omicron. Front Immunol. 2023 Nov 10;14:1271209.
Rowell MC, Deschênes-Simard X, Lopes-Paciencia S, Le Calvé B, Kalegari P, Mignacca L, Fernandez-Ruiz A, Guillon J, Lessard F, Bourdeau V, Igelmann S, Duman AM, Stanom Y, Kottakis F, Deshpande V, Krizhanovsky V, Bardeesy N, Ferbeyre G. Targeting ribosome biogenesis reinforces ERK-dependent senescence in pancreatic cancer. Cell Cycle. 2023 Nov 9:1-22.
Gemeinhardt TM, Regy RM, Mendiola AJ, Ledterman HJ, Henrickson A, Phan TM, Kim YC, Demeler B, Kim CA, Mittal J, Francis NJ. How a disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization. bioRxiv. 2023 Oct 27:2023.10.26.564264.
Rouleau-Turcotte É, Pascal JM. ADP-ribose contributions to genome stability, and PARP enzyme trapping on sites of DNA damage; paradigm shifts for a coming-of-age modification. J Biol Chem. 2023 Oct 26:105397.
Pinard M, Moursli A, Coulombe B. Drugs targeting the particle for arrangement of quaternary structure (PAQosome) and protein complex assembly. Expert Opin Drug Discov. 2023 Oct 15:1-15.
Wright SC, Motso A, Koutsilieri S, Beusch CM, Sabatier P, Berghella A, Blondel-Tepaz É, Mangenot K, Pittarokoilis I, Sismanoglou DC, Le Gouill C, Olsen JV, Zubarev RA, Lambert NA, Hauser AS, Bouvier M, Lauschke VM. GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics. Nat Commun. 2023 Oct 9;14(1):6243.
Macintosh J, Perrier S, Pinard M, Tran LT, Guerrero K, Prasad C, Prasad AN, Pastinen T, Thiffault I, Coulombe B, Bernard G. Biallelic pathogenic variants in POLR3D alter tRNA transcription and cause a hypomyelinating leukodystrophy: A case report. Front Neurol. 2023 Oct 13;14:1254140.
Stuible M, Schrag JD, Sheff J, Zoubchenok D, Lord-Dufour S, Cass B, L’Abbé D, Pelletier A, Rossotti MA, Tanha J, Gervais C, Maurice R, El Bakkouri M, Acchione M, Durocher Y. Influence of variant-specific mutations, temperature and pH on conformations of a large set of SARS-CoV-2 spike trimer vaccine antigen candidates. Sci Rep. 2023 Oct 1;13(1):16498.
Burghi V, Paradis JS, Officer A, Adame Garcia S, Wu X, Matthees ES, Barsi-Rhyne B, Ramms DJ, Clubb L, Acosta M, Tamayo P, Bouvier M, Inoue A, von Zastrow M, Hoffmann C, Gutkind JS. Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor. J Biol Chem. 2023 Sep 27:105293.
Bulyk ML, Drouin J, Harrison MM, Taipale J, Zaret KS. Pioneer factors – key regulators of chromatin and gene expression. Nat Rev Genet. 2023 Sep 22. doi: 10.1038/s41576-023-00648-z.
Padilla JA, Barutcu S, Malet L, Deschamps-Francoeur G, Calderon V, Kwon E, Lécuyer E. Profiling the polyadenylated transcriptome of extracellular vesicles with long-read nanopore sequencing. BMC Genomics. 2023 Sep 22;24(1):564.
Limoges MA, Quenum AJI, Chowdhury MMH, Rexhepi F, Namvarpour M, Akbari SA, Rioux-Perreault C, Nandi M, Lucier JF, Lemaire-Paquette S, Premkumar L, Durocher Y, Cantin A, Lévesque S, Dionne IJ, Menendez A, Ilangumaran S, Allard-Chamard H, Piché A, Ramanathan S. SARS-CoV-2 spike antigen-specific B cell and antibody responses in pre-vaccination period COVID-19 convalescent males and females with or without post-covid condition. Front Immunol. 2023 Sep 21;14:1223936.
Sauvageau J, Koyuturk I, St Michael F, Brochu D, Goneau MF, Schoenhofen I, Perret S, Star A, Robotham A, Haqqani A, Kelly J, Gilbert M, Durocher Y. Simplifying glycan monitoring of complex antigens such as the SARS-CoV-2 spike to accelerate vaccine development. Commun Chem. 2023 Sep 8;6(1):189.
Normandin K, Coulombe-Huntington J, St-Denis C, Bernard A, Bourouh M, Bertomeu T, Tyers M, Archambault V. Genetic enhancers of partial PLK1 inhibition reveal hypersensitivity to kinetochore perturbations. PLoS Genet. 2023 Aug 28;19(8):e1010903. doi: 10.1371/journal.pgen.1010903.
Michell-Robinson MA, Watt KEN, Grouza V, Macintosh J, Pinard M, Tuznik M, Chen X, Darbelli L, Wu CL, Perrier S, Chitsaz D, Uccelli NA, Liu H, Cox TC, Müller CW, Kennedy TE, Coulombe B, Rudko DA, Trainor PA, Bernard G. Hypomyelination, hypodontia and craniofacial abnormalities in a Polr3b mouse model of leukodystrophy. Brain. 2023 Aug 28:awad249. doi: 10.1093/brain/awad249.
Alpuche-Lazcano SP, Stuible M, Akache B, Tran A, Kelly J, Hrapovic S, Robotham A, Haqqani A, Star A, Renner TM, Blouin J, Maltais JS, Cass B, Cui K, Cho JY, Wang X, Zoubchenok D, Dudani R, Duque D, McCluskie MJ, Durocher Y. Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells. Commun Med (Lond). 2023 Aug 23;3(1):116.
Cuevas MVR, Hardy MP, Larouche JD, Apavaloaei A, Kina E, Vincent K, Gendron P, Laverdure JP, Durette C, Thibault P, Lemieux S, Perreault C, Ehx G. BamQuery: a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens. Genome Biol. 2023 Aug 15;24(1):188.
Dégardin M, Liberelle B, Oliverio R, Baniahmad SF, Darviot C, Largillière I, Henry O, Durocher Y, Banquy X, Meunier M, De Crescenzo G. Coiled-Coil-Based Biofunctionalization of 100 nm Gold Nanoparticles with the Trastuzumab Antibody for the Detection of HER2-Positive Cancer Cells. Langmuir. 2023 Aug 15. doi: 10.1021/acs.langmuir.3c01621.
Perera DJ, Domenech P, Babuadze GG, Naghibosadat M, Alvarez F, Koger-Pease C, Labrie L, Stuible M, Durocher Y, Piccirillo CA, Lametti A, Fiset PO, Elahi SM, Kobinger GP, Gilbert R, Olivier M, Kozak R, Reed MB, Ndao M. BCG administration promotes the long-term protection afforded by a single-dose intranasal adenovirus-based SARS-CoV-2 vaccine. iScience. 2023 Aug 11;26(9):107612.
Scicluna M, Grenier JC, Poujol R, Lemieux S, Hussin JG. Toward computing attributions for dimensionality reduction techniques. Bioinform Adv. 2023 Aug 3;3(1):vbad097.
Záhonová K, Valach M, Tripathi P, Benz C, Opperdoes FR, Barath P, Lukáčová V, Danchenko M, Faktorová D, Horváth A, Burger G, Lukeš J, Škodová-Sveráková I. Subunit composition of mitochondrial dehydrogenase complexes in diplonemid flagellates. Biochim Biophys Acta Gen Subj. 2023 Jul 12:130419.
Lang BF, Beck N, Prince S, Sarrasin M, Rioux P, Burger G. Mitochondrial genome annotation with MFannot: a critical analysis of gene identification and gene model prediction. Front Plant Sci. 2023 Jul 4;14:1222186.
Emond-Fraser V, Larouche M, Kubiniok P, Bonneil É, Li J, Bourouh M, Frizzi L, Thibault P, Archambault V. Identification of PP2A-B55 targets uncovers regulation of emerin during nuclear envelope reassembly in Drosophila. Open Biol. 2023 Jul;13(7):230104.
Pascal JM. PARP-nucleic acid interactions: Allosteric signaling, PARP inhibitor types, DNA bridges, and viral RNA surveillance. Curr Opin Struct Biol. 2023 Jun 21;81:102643.
Bascunana V, Pelletier A, Gouhier A, Bemmo A, Balsalobre A, Drouin J. Chromatin opening ability of pioneer factor Pax7 depends on unique isoform and C-terminal domain. Nucleic Acids Res. 2023 Jun 16:gkad520.
Bensidoun P, Zenklusen D, Oeffinger M. Differential affinity purification and mass spectrometry analysis of two nuclear pore complex isoforms in yeast S. cerevisiae. STAR Protoc. 2023 Jun 15;4(3):102359.
Audray Fortin, Marc Veillette, Adriana Larrotta, Yves Longtin, Caroline Duchaine, Nathalie Grandvaux. Detection of viable SARS-CoV-2 in retrospective analysis of aerosol samples collected from hospital rooms of patients with COVID-19. Clin Microbiol Infect. 2023 Jun;29(6):805-807.
Maltais JS, Lord-Dufour S, Morasse A, Stuible M, Loignon M, Durocher Y. Repressing expression of difficult-to-express recombinant proteins during the selection process increases productivity of CHO stable pools. Biotechnol Bioeng. 2023 May 26. doi: 10.1002/bit.28435.
Shaferman M, Gencel M, Alon N, Alasad K, Rotblat B, Serohijos AWR, Alfonta L, Bershtein S. The fitness effects of codon composition of the horizontally transferred antibiotic resistance genes intensify at sub-lethal antibiotic levels. Mol Biol Evol. 2023 May 23:msad123.
Valach M, Benz C, Aguilar LC, Gahura O, Faktorová D, Zíková A, Oeffinger M, Burger G, Gray MW, Lukeš J. Miniature RNAs are embedded in an exceptionally protein-rich mitoribosome via an elaborate assembly pathway. Nucleic Acids Res. 2023 May 19:gkad422.
Ravindran R, Bacellar IOL, Castellanos-Girouard X, Wahba HM, Zhang Z, Omichinski JG, Kisley L, Michnick SW. Peroxisome biogenesis initiated by protein phase separation. Nature. 2023 May;617(7961):608-615.
Valach M, Moreira S, Petitjean C, Benz C, Butenko A, Flegontova O, Nenarokova A, Prokopchuk G, Batstone T, Lapébie P, Lemogo L, Sarrasin M, Stretenowich P, Tripathi P, Yazaki E, Nara T, Henrissat B, Lang BF, Gray MW, Williams TA, Lukeš J, Burger G. Recent expansion of metabolic versatility in Diplonema papillatum, the model species of a highly speciose group of marine eukaryotes. BMC Biol. 2023 May 4;21(1):99.
Meharwade T, Joumier L, Parisotto M, Huynh V, Lummertz da Rocha E, Malleshaiah M. Cross-activation of FGF, NODAL, and WNT pathways constrains BMP-signaling-mediated induction of the totipotent state in mouse embryonic stem cells. Cell Rep. 2023 Apr 30;42(5):112438.
Renner TM, Akache B, Stuible M, Rohani N, Cepero-Donates Y, Deschatelets L, Dudani R, Harrison BA, Baardsnes J, Koyuturk I, Hill JJ, Hemraz UD, Régnier S, Lenferink AEG, Durocher Y, McCluskie MJ. Tuning the immune response: sulfated archaeal glycolipid archaeosomes as an effective vaccine adjuvant for induction of humoral and cell-mediated immunity towards the SARS-CoV-2 Omicron variant of concern. Front Immunol. 2023 Apr 14;14:1182556.
Kaur S, Sokrat B, Capozzi ME, El K, Bai Y, Jazic A, Han B, Krishnakumar K, D’Alessio DA, Campbell JE, Bouvier M, Shenoy SK. The Ubiquitination Status of the Glucagon Receptor determines Signal Bias. J Biol Chem. 2023 Apr 8:104690.
Joubert S, Stuible M, Lord-Dufour S, Lamoureux L, Vaillancourt F, Perret S, Ouimet M, Pelletier A, Bisson L, Mahimkar R, Pham PL, L Ecuyer-Coelho H, Roy M, Voyer R, Baardsnes J, Sauvageau J, St-Michael F, Robotham A, Kelly J, Acel A, Schrag JD, El Bakkouri M, Durocher Y. A CHO stable pool production platform for rapid clinical development of trimeric SARS-CoV-2 spike subunit vaccine antigens. Biotechnol Bioeng. 2023 Mar 29. doi: 10.1002/bit.28387.
Langelier MF, Lin X, Zha S, Pascal JM. Clinical PARP inhibitors allosterically induce PARP2 retention on DNA. Sci Adv. 2023 Mar 24;9(12):eadf7175.
Drouin JR, Rojas JA. Influence of face masks on recalibration of phonetic categories. Atten Percept Psychophys. 2023 May 15:1-18.
Farajzadeh N, Shahbabian K, Bouaziz Y, Querido E, Chartrand P. Phosphorylation controls the oligomeric state of She2 and mRNA localization in yeast. RNA. 2023 Mar 15:rna.079555.122.
González L, Kolbin D, Trahan C, Jeronimo C, Robert F, Oeffinger M, Bloom K, Michnick SW. Adaptive partitioning of a gene locus to the nuclear envelope in Saccharomyces cerevisiae is driven by polymer-polymer phase separation. Nat Commun. 2023 Feb 28;14(1):1135.
Laspata N, Kaur P, Mersaoui SY, Muoio D, Liu ZS, Bannister MH, Nguyen HD, Curry C, Pascal JM, Poirier GG, Wang H, Masson JY, Fouquerel E. PARP1 associates with R-loops to promote their resolution and genome stability. Nucleic Acids Res. 2023 Feb 16:gkad066.
Nepotchatykh E, Caraus I, Elremaly W, Leveau C, Elbakry M, Godbout C, Rostami-Afshari B, Petre D, Khatami N, Franco A, Moreau A. Circulating microRNA expression signatures accurately discriminate myalgic encephalomyelitis from fibromyalgia and comorbid conditions. Sci Rep. 2023 Feb 2;13(1):1896.
Natalia Zamorano Cuervo, Nathalie Grandvaux. Redox proteomics and structural analyses provide insightful implications for additional non-catalytic thiol-disulfide motifs in PDIs. Redox Biol. 2023 Feb;59:102583.
Dacquin M Kasumba, Sandrine Huot, Elise Caron, Audray Fortin, Cynthia Laflamme, Natalia Zamorano Cuervo, Felix Lamontagne, Marc Pouliot, Nathalie Grandvaux. DUOX2 regulates secreted factors in virus-infected respiratory epithelial cells that contribute to neutrophil attraction and activation. FASEB J. 2023 Feb;37(2):e22765.
Khan MGM, Boufaied N, Yeganeh M, Kandhi R, Petkiewicz S, Sharma A, Yoshimura A, Ferbeyre G, Labbé DP, Ramanathan S, Ilangumaran S. SOCS1 Deficiency Promotes Hepatocellular Carcinoma via SOCS3-Dependent CDKN1A Induction and NRF2 Activation. Cancers (Basel). 2023 Jan 31;15(3):905.
Djaïleb A, Lavallée É, Parker MF, Cayer MP, Desautels F, de Grandmont MJStuible M, Gervais C, Durocher Y, Trottier S, Boudreau D, Masson JF, Brouard D, Pelletier JN. Assessment of the longitudinal humoral response in non-hospitalized SARS-CoV-2-positive individuals at decentralized sites: Outcomes and concordance. Front Immunol. 2023 Jan 20;13:1052424.
Thimmappa BC, Salhi LN, Forget L, Sarrasin M, Bustamante Villalobos P, Lang BF, Burger G. Nuclear Genome Sequence and Gene Expression of an Intracellular Fungal Endophyte Stimulating the Growth of Cranberry Plants. J Fungi (Basel). 2023 Jan 16;9(1):126.
Benoit Bouvrette LP, Wang X, Boulais J, Kong J, Syed EU, Blue SM, Zhan L, Olson S, Stanton R, Wei X, Yee B, Van Nostrand EL, Fu XD, Burge CB, Graveley BR, Yeo GW, Lécuyer E. RBP Image Database: A resource for the systematic characterization of the subcellular distribution properties of human RNA binding proteins. Nucleic Acids Res. 2023 Jan 6;51(D1):D1549-D1557.
Jaramillo ML, Sulea T, Durocher Y, Acchione M, Schur MJ, Robotham A, Kelly JF, Goneau MF, Robert A, Cepero-Donates Y, Gilbert M. A glyco-engineering approach for site-specific conjugation to Fab glycans. MAbs. 2023 Jan-Dec;15(1):2149057.
Butani N, Xu Y, Pan S, Durocher Y, Ghosh R. A fast, efficient, and scalable method for purifying recombinant SARS-CoV-2 spike protein. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Jan 15;1215:123579.
Vallet A, El Ezzy M, Diennet M, Haidar S, Bouvier M, Mader S. The AF-2 cofactor binding region is key for the selective SUMOylation of estrogen receptor alpha by antiestrogens. J Biol Chem. 2023 Jan;299(1):102757.
Trahan C, Oeffinger M. The Importance of Being RNA-est: considering RNA-mediated ribosome plasticity. RNA Biol. 2023 Jan;20(1):177-185.
Oeffinger M. A special issue dedicated to the memory of Jonathan R. Warner (1936-2019), a pioneer of ribosome biology. RNA Biol. 2023 Jan;20(1):306.
Oeffinger M. Special focus on the ribosome life cycle. RNA Biol. 2023 Jan;20(1):307-310.
Baniahmad SF, Oliverio R, Obregon-Gomez I, Robert A, Lenferink AEG, Pazos E, Virgilio N, Banquy X, De Crescenzo G, Durocher Y. Affinity-controlled capture and release of engineered monoclonal antibodies by macroporous dextran hydrogels using coiled-coil interactions. MAbs. 2023 Jan-Dec;15(1):2218951.
Gaitonde SA, Bouvier M. Enhanced Bystander BRET (ebBRET) Biosensors as Biophysical Tools to Map the Signaling Profile of Neuropsychiatric Drugs Targeting GPCRs. Methods Mol Biol. 2023;2687:15-30.