Distinctions et publications

Publications 2021

Kobayashi H, Bouvier M. Bioluminescence Resonance Energy Transfer (BRET) Imaging in Living Cells: Image Acquisition and Quantification. Methods Mol Biol. 2021;2274:305-314.

Fellouse FA, Miersch S, Chen C, Michnick SW. Structure-based Design of a Specific, Homogeneous Luminescence Enzyme Reporter Assay for SARS-CoV-2. J Mol Biol. 2021 Jun 25;433(13):166983.

N’Guessan A, Brito IL, Serohijos AWR, Shapiro BJ. Mobile gene sequence evolution within individual human gut microbiomes is better explained by gene-specific than host-specific selective pressures. Genome Biol Evol. 2021 Jun 16:evab142.

Trauelsen M, Hiron TK, Lin D, Petersen JE, Breton B, Husted AS, Hjorth SA, Inoue A, Frimurer TM, Bouvier M, O’Callaghan CA, Schwartz TW. Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling. Cell Rep. 2021 Jun 15;35(11):109246.

Sidibé H, Khalfallah Y, Xiao S, Gómez NB, Fakim H, Tank EMH, Tomasso GD, Bareke E, Aulas A, McKeever PM, Melamed Z, Destroimaisons L, Deshaies JE, Zinman L, Parker JA, Legault P, Tétreault M, Barmada SJ, Robertson J, Velde CV. TDP-43 stabilizes G3BP1 mRNA: relevance to amyotrophic lateral sclerosis/frontotemporal dementia. Brain. 2021 Jun 11:awab217.

Mancini OK, Acevedo M, Fazez N, Cuillerier A, Ruiz AF, Huynh DN, Burelle Y, Ferbeyre G, Baron M, Servant MJ. Oxidative stress-induced senescence mediates inflammatory and fibrotic phenotypes in fibroblasts from systemic sclerosis patients. Rheumatology (Oxford). 2021 Jun 11:keab477.

Larouche M, Kachaner D, Wang P, Normandin K, Garrido D, Yao C, Cormier M, Johansen KM, Johansen J, Archambault V. Spatiotemporal coordination of Greatwall-Endos-PP2A promotes mitotic progression. J Cell Biol. 2021 Jun 7;220(6):e202008145.

Henry KA, Nguyen TD, Baral TN, Hussack G, Raphael S, Arbabi-Ghahroudi M, Robert A, Durocher Y, Wu C, Jaramillo ML, MacKenzie CR. Biparatopic single-domain antibodies against Axl achieve ultra-high affinity through intramolecular engagement. Biochem Biophys Res Commun. 2021 May 28;562:154-161.

Wright SC, Bouvier M. Illuminating the complexity of GPCR pathway selectivity – advances in biosensor development. Curr Opin Struct Biol. 2021 May 25;69:142-149.

Bonnet-Magnaval F, DesGroseillers L. The Staufen1-dependent cell cycle regulon or how a misregulated RNA-binding protein leads to cancer. Biol Rev Camb Philos Soc. 2021 May 20. doi: 10.1111/brv.12749.

Karine Tremblay, Simon Rousseau, Ma’n H Zawati, Daniel Auld, Michaël Chassé, Daniel Coderre, Emilia Liana Falcone, Nicolas Gauthier, Nathalie Grandvaux, François Gros-Louis, Carole Jabet, Yann Joly, Daniel E Kaufmann, Catherine Laprise, Catherine Larochelle, François Maltais, Anne-Marie Mes-Masson, Alexandre Montpetit, Alain Piché, J Brent Richards, Sze Man Tse, Alexis F Turgeon, Gustavo Turecki, Donald C Vinh, Han Ting Wang, Vincent Mooser, BQC19. The Biobanque québécoise de la COVID-19 (BQC19)—A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories. PLoS One. 2021 May 19;16(5):e0245031.

Wright SC, Lukasheva V, Le Gouill C, Kobayashi H, Breton B, Mailhot-Larouche S, Blondel-Tepaz É, Antunes Vieira N, Costa-Neto C, Héroux M, Lambert NA, Parreiras-E-Silva LT, Bouvier M. BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated Gq activation at early endosomes. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2025846118.

Hébert A, Parisotto M, Rowell MC, Doré A, Fernandez Ruiz A, Lefrançois G, Kalegari P, Ferbeyre G, Schmitzer AR. Phenylethynylbenzyl-modified biguanides inhibit pancreatic cancer tumor growth. Sci Rep. 2021 May 10;11(1):9854.

Bensidoun P, Zenklusen D, Oeffinger M. Choosing the right exit: How functional plasticity of the nuclear pore drives selective and efficient mRNA export. Wiley Interdiscip Rev RNA. 2021 May 2:e1660.

Razban RM, Dasmeh P, Serohijos AWR, Shakhnovich EI. Avoidance of protein unfolding constrains protein stability in long-term evolution. Biophys J. 2021 Apr 28:S0006-3495(21)00340-4.

Natalia Zamorano Cuervo, Audray Fortin, Elise Caron, Stéfany Chartier, Nathalie Grandvaux. Pinpointing cysteine oxidation sites by high-resolution proteomics reveals a mechanism of redox-dependent inhibition of human STING. Sci Signal. 2021 Apr 27;14(680):eaaw4673.

de Melo Teixeira M, Lang BF, Matute DR, Stajich JE, Barker B. The mitochondrial genomes of the human pathogens Coccidioides immitis and C. posadasii. G3 (Bethesda). 2021 Apr 19:jkab132.

Fellouse FA, Miersch S, Chen C, Michnick SW. Structure-Based Design of a Specific, Homogeneous Luminescence Enzyme Reporter Assay for SARS-CoV-2. J Mol Biol. 2021 Apr 8:166983. doi: 10.1016/j.jmb.2021.166983.

Liu X, Chai Y, Liu G, Su W, Guo Q, Lv X, Gao P, Yu B, Ferbeyre G, Cao X, Wan M. Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis. Nat Commun. 2021 Mar 23;12(1):1832.

Brouwers B, de Oliveira EM, Marti-Solano M, Monteiro FBF, Laurin SA, Keogh JM, Henning E, Bounds R, Daly CA, Houston S, Ayinampudi V, Wasiluk N, Clarke D, Plouffe B, Bouvier M, Babu MM, Farooqi IS, Mokrosiński J. Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation. Cell Rep. 2021 Mar 23;34(12):108862.

Meyrath M, Palmer CB, Reynders N, Vanderplasschen A, Ollert M, Bouvier M, Szpakowska M, Chevigné A. Proadrenomedullin N-Terminal 20 Peptides (PAMPs) Are Agonists of the Chemokine Scavenger Receptor ACKR3/CXCR7. ACS Pharmacol Transl Sci. 2021 Mar 22;4(2):813-823.

Leguay K, Decelle B, He YY, Pagniez A, Hogue M, Kobayashi H, Le Gouill C, Bouvier M, Carréno S. Development of conformational BRET biosensors that monitor ezrin, radixin and moesin activation in real-time. J Cell Sci. 2021 Mar 12:jcs.255307.

Grunddal KV, Diep TA, Petersen N, Tough IR, Skov LJ, Liu L, Buijink JA, Mende F, Jin C, Jepsen SL, Sørensen LME, Achiam MP, Strandby RB, Bach A, Hartmann B, Frimurer TM, Hjorth SA, Bouvier M, Cox H, Holst B. Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist. Mol Metab. 2021 Mar 9:101207.

Gargalovic P, Wong P, Onorato J, Finlay H, Wang T, Yan M, Crain E, St-Onge S, Héroux M, Bouvier M, Xu C, Chen XQ, Generaux C, Lawrence M, Wexler R, Gordon D. In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure. Circ Heart Fail. 2021 Mar 5:CIRCHEARTFAILURE120007351.

Condé L, Gonzalez Quesada Y, Bonnet-Magnaval F, Beaujois R, DesGroseillers L. STAU2 protein level is controlled by caspases and the CHK1 pathway and regulates cell cycle progression in the non-transformed hTERT-RPE1 cells. BMC Mol Cell Biol. 2021 Mar 4;22(1):16.

Bury M, Le Calvé B, Ferbeyre G, Blank V, Lessard F. New Insights into CDK Regulators: Novel Opportunities for Cancer Therapy. Trends Cell Biol. 2021 Mar 3:S0962-8924(21)00025-8.

Blondel-Tepaz E, Leverve M, Sokrat B, Paradis JS, Kosic M, Saha K, Auffray C, Lima-Fernandes E, Zamborlini A, Poupon A, Gaboury L, Findlay J, Baillie GS, Enslen H, Bouvier M, Angers S, Marullo S, Scott MGH. The RanBP2/RanGAP1-SUMO complex gates β-arrestin2 nuclear entry to regulate the Mdm2-p53 signaling axis. Oncogene. 2021 Mar 1. doi: 10.1038/s41388-021-01704-w.

Knüppel R, Trahan C, Kern M, Wagner A, Grünberger F, Hausner W, Quax TEF, Albers SV, Oeffinger M, Ferreira-Cerca S. Insights into synthesis and function of KsgA/Dim1-dependent rRNA modifications in archaea. Nucleic Acids Res. 2021 Feb 22;49(3):1662-1687.

Genois MM, Gagné JP, Yasuhara T, Jackson J, Saxena S, Langelier MF, Ahel I, Bedford MT, Pascal JM, Vindigni A, Poirier GG, Zou L. CARM1 regulates replication fork speed and stress response by stimulating PARP1. Mol Cell. 2021 Feb 18;81(4):784-800.e8.

Gaudreault J, Liberelle B, Durocher Y, Henry O, De Crescenzo G. Determination of the composition of heterogeneous binder solutions by surface plasmon resonance biosensing. Sci Rep. 2021 Feb 11;11(1):3685.

Jayabalan AK, Adivarahan S, Koppula A, Abraham R, Batish M, Zenklusen D, Griffin DE, Leung AKL. Stress granule formation, disassembly, and composition are regulated by alphavirus ADP-ribosylhydrolase activity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2021719118.

Tschaikner P, Regele D, Röck R, Salvenmoser W, Meyer D, Bouvier M, Geley S, Stefan E, Aanstad P. Feedback Control of the Gpr161-Gαs-PKA axis contributes to basal Hedgehog repression in zebrafish. Development. 2021 Feb 2:dev.192443.

Trân K, Van Den Hauwe R, Sainsily X, Couvineau P, Côté J, Simard L, Echevarria M, Murza A, Serre A, Théroux L, Saibi S, Haroune L, Longpré JM, Lesur O, Auger-Messier M, Spino C, Bouvier M, Sarret P, Ballet S, Marsault É. Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile. J Med Chem. 2021 Feb 1. doi: 10.1021/acs.jmedchem.0c01941.

Dodat F, Cotnoir-White D, Dianati E, Vallet A, Mader S, Lévesque D. Complex regulation of orphan nuclear receptor Nur77 (Nr4a1) transcriptional activity by SUMO2 and PIASγ. Biochim Biophys Acta Mol Cell Res. 2021 Feb;1868(2):118908.

Ogden TEH, Yang JC, Schimpl M, Easton LE, Underwood E, Rawlins PB, McCauley MM, Langelier MF, Pascal JM, Embrey KJ, Neuhaus D. Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition. Nucleic Acids Res. 2021 Jan 28:gkab020.

Stuible M, Gervais C, Lord-Dufour S, Perret S, L’Abbé D, Schrag J, St-Laurent G, Durocher Y. Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells. J Biotechnol. 2021 Jan 20;326:21-27.

Trân K, Murza A, Sainsily X, Delile E, Couvineau P, Côté J, Coquerel D, Peloquin M, Auger-Messier M, Bouvier M, Lesur O, Sarret P, Marsault É. Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor. J Med Chem. 2021 Jan 14;64(1):602-615.

Knüppel R, Trahan C, Kern M, Wagner A, Grünberger F, Hausner W, Quax TEF, Albers SV, Oeffinger M, Ferreira-Cerca S. Insights into synthesis and function of KsgA/Dim1-dependent rRNA modifications in archaea. Nucleic Acids Res. 2021 Jan 12:gkaa1268.

Hammel M, Rashid I, Sverzhinsky A, Pourfarjam Y, Tsai MS, Ellenberger T, Pascal JM, Kim IK, Tainer JA, Tomkinson AE. An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex. Nucleic Acids Res. 2021 Jan 11;49(1):306-321.

René P, Lanfray D, Richard D, Bouvier M. Pharmacological chaperone action in humanized mouse models of MC4R-linked obesity. JCI Insight. 2021 Jan 12:132778.

Van Nostrand EL, Freese P, Pratt GA, Wang X, Wei X, Xiao R, Blue SM, Chen JY, Cody NAL, Dominguez D, Olson S, Sundararaman B, Zhan L, Bazile C, Bouvrette LPB, Bergalet J, Duff MO, Garcia KE, Gelboin-Burkhart C, Hochman M, Lambert NJ, Li H, McGurk MP, Nguyen TB, Palden T, Rabano I, Sathe S, Stanton R, Su A, Wang R, Yee BA, Zhou B, Louie AL, Aigner S, Fu XD, Lécuyer E, Burge CB, Graveley BR, Yeo GW. A large-scale binding and functional map of human RNA-binding proteins. Nature. 2021 Jan 5. doi: 10.1038/s41586-020-03067-w.

Adivarahan S, Zenklusen D. Probing the Conformational State of mRNPs Using smFISH and SIM. Methods Mol Biol. 2021; 2209:267-286.

Dagenais P, Legault P. In Vitro Selection of Varkud Satellite Ribozyme Variants that Cleave a Modified Stem-Loop Substrate. Methods Mol Biol. 2021;2167:61-77.

Publications 2020

Genois MM, Gagné JP, Yasuhara T, Jackson J, Saxena S, Langelier MF, Ahel I, Bedford MT, Pascal JM, Vindigni A, Poirier GG, Zou L. CARM1 regulates replication fork speed and stress response by stimulating PARP1. Mol Cell. 2020 Dec 30:S1097-2765(20)30902-3.

Trân K, Murza A, Sainsily X, Delile E, Couvineau P, Côté J, Coquerel D, Peloquin M, Auger-Messier M, Bouvier M, Lesur O, Sarret P, Marsault É. Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor. J Med Chem. 2020 Dec 22. doi: 10.1021/acs.jmedchem.0c01547.

Simões SC, Balico-Silva AL, Parreiras-E-Silva LT, Bitencourt ALB, Bouvier M, Costa-Neto CM. Signal Transduction Profiling of Angiotensin II Type 1 Receptor With Mutations Associated to Atrial Fibrillation in Humans. Front Pharmacol. 2020 Dec 22;11:600132.

Hammel M, Rashid I, Sverzhinsky A, Pourfarjam Y, Tsai MS, Ellenberger T, Pascal JM, Kim IK, Tainer JA, Tomkinson AE. An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex. Nucleic Acids Res. 2020 Dec 16:gkaa1188.

Corrêa MF, Balico-Silva AL, Kiss DJ, Fernandes GAB, Maraschin JC, Parreiras-E-Silva LT, Varela MT, Simões SC, Bouvier M, Keserű GM, Costa-Neto CM, Fernandes JPS.  Novel potent (dihydro)benzofuranyl piperazines as human histamine receptor ligands – Functional characterization and modeling studies on H3 and H4 receptors. Bioorg Med Chem. 2020 Dec 8;30:115924.

Latorraca NR, Masureel M, Hollingsworth SA, Heydenreich FM, Suomivuori CM, Brinton C, Townshend RJL, Bouvier M, Kobilka BK, Dror RO. How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling. Cell. 2020 Dec 8:S0092-8674(20)31531-2.

Serrano D, Cordero G, Kawamura R, Sverzhinsky A, Sarker M, Roy S, Malo C, Pascal JM, Marko JF, D’Amours D. The Smc5/6 Core Complex Is a Structure-Specific DNA Binding and Compacting Machine. Mol Cell. 2020 Dec 7:S1097-2765(20)30789-9.

Stuible M, Gervais C, Lord-Dufour S, Perret S, L’Abbé D, Schrag J, St-Laurent G, Durocher Y. Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells. J Biotechnol. 2020 Dec 7:S0168-1656(20)30327-8.

Moiseeva O, Guillon J, Ferbeyre G. Senescence: a program in the road to cell elimination and cancer. Semin Cancer Biol. 2020 Dec 23:S1044-579X(20)30277-7.

Avet C, Sturino C, Grastilleur S, Gouill CL, Semache M, Gross F, Gendron L, Bennani Y, Mancini JA, Sayegh CE, Bouvier M. The PAR2 inhibitor I-287 selectively targets Gαq and Gα12/13 signaling and has anti-inflammatory effects. Commun Biol. 2020 Nov 27;3(1):719.

Rouleau-Turcotte É, Pascal JM. Bridging a DNA Break to Leave a Poly(ADP-Ribose) Mark on Chromatin. Mol Cell. 2020 Nov 19;80(4):560-561.

Dodat F, Cotnoir-White D, Dianati E, Vallet A, Mader S, Lévesque D. Complex regulation of orphan nuclear receptor Nur77 (Nr4a1) transcriptional activity by SUMO2 and PIASγ. Biochim Biophys Acta Mol Cell Res. 2020 Nov 12:118908.

Nepotchatykh E, Elremaly W, Caraus I, Godbout C, Leveau C, Chalder L, Beaudin C, Kanamaru E, Kosovskaia R, Lauzon S, Maillet Y, Franco A, Lascau-Coman V, Bouhanik S, Gaitan YP, Li D, Moreau A. Profile of circulating microRNAs in myalgic encephalomyelitis and their relation to symptom severity, and disease pathophysiology. Sci Rep. 2020 Nov 12;10(1):19620.

Natalia Zamorano Cuervo , Nathalie Grandvaux. ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities. Elife. 2020 Nov 9;9:e61390.

Matsumoto Y, Brooks RC, Sverzhinsky A, Pascal JM, Tomkinson AE. Dynamic DNA-bound PCNA complexes co-ordinate Okazaki fragment synthesis, processing and ligation. J Mol Biol. 2020 Nov 3:S0022-2836(20)30616-1.

Aguilar LC, Paul B, Reiter T, Gendron L, Arul Nambi Rajan A, Montpetit R, Trahan C, Pechmann S, Oeffinger M, Montpetit B. Altered rRNA processing disrupts nuclear RNA homeostasis via competition for the poly(A)-binding protein Nab2. Nucleic Acids Res. 2020 Nov 2:gkaa964.

Garrido D, Bourouh M, Bonneil É, Thibault P, Swan A, Archambault V. Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis. PLoS Genet. 2020 Nov 2;16(11):e1009184.

Møller TC, Pedersen MF, van Senten JR, Seiersen SD, Mathiesen JM, Bouvier M, Bräuner-Osborne H. Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells. Sci Rep. 2020 Oct 15;10(1):17395.

Imam A, Winnebeck EC, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study. Front Physiol. 2020 Oct 9;11:564140.

Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras AC. Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. Sci Immunol. 2020 Oct 8;5(52):eabe5511.

Abe KT, Li Z, Samson R, Samavarchi-Tehrani P, Valcourt EJ, Wood H, Budylowski P, Dupuis AP 2nd, Girardin RC, Rathod B, Wang JH, Barrios-Rodiles M, Colwill K, McGeer AJ, Mubareka S, Gommerman JL, Durocher Y, Ostrowski M, McDonough KA, Drebot MA, Drews SJ, Rini JM, Gingras AC. A simple protein-based surrogate neutralization assay for SARS-CoV-2. JCI Insight. 2020 Oct 2;5(19):142362.

Quattrocchi V, Bidart J, Mignaqui AC, Ruiz V, Ferella A, Langellotti C, Gammella M, Ferraris S, Carrillo J, Wigdorovitz A, Durocher Y, Cardillo SB, Charleston B, Zamorano PI. Bovine Dendritic Cell Activation, T Cell Proliferation and Antibody Responses to Foot-And-Mouth Disease, Is Similar With Inactivated Virus and Virus Like Particles. Front Vet Sci. 2020 Sep 30;7:594.

Chin A, Lécuyer E. Translating Messages in Different Neighborhoods. Dev Cell. 2020 Sep 28;54(6):691-693.

Smith M, Querido E, Chartrand P, Sfeir A. Quantitative Imaging of MS2-Tagged hTR in Cajal Bodies: Photobleaching and Photoactivation. STAR Protoc. 2020 Sep 24;1(3):100112.

Mignaqui AC, Ferella A, Cass B, Mukankurayija L, L’Abbé D, Bisson L, Sánchez C, Scian R, Cardillo SB, Durocher Y, Wigdorovitz A. Foot-and-Mouth Disease: Optimization, Reproducibility, and Scalability of High-Yield Production of Virus-Like Particles for a Next-Generation Vaccine. Front Vet Sci. 2020 Sep 23;7:601.

Chartrand P, Sfeir A. A single-molecule view of telomerase regulation at telomeres. Mol Cell Oncol. 2020 Sep 20;7(6):1818537.

Fabre L, Ntreh AT, Yazidi A, Leus IV, Weeks JW, Bhattacharyya S, Ruickoldt J, Rouiller I, Zgurskaya HI, Sygusch J. A « Drug Sweeping » State of the TriABC Triclosan Efflux Pump from Pseudomonas aeruginosa. Structure. 2020 Sep 15:S0969-2126(20)30326-9.

Kouwenhoven WM, Fortin G, Penttinen AM, Florence C, Delignat-Lavaud B, Bourque MJ, Trimbuch T, Luppi MP, Salvail-Lacoste A, Legault P, Poulin JF, Rosenmund C, Awatramani R, Trudeau LÉ. VGLUT2 EXPRESSION IN DOPAMINE NEURONS CONTRIBUTES TO POST-LESIONAL STRIATAL REINNERVATION. J Neurosci. 2020 Sep 14:JN-RM-0823-20.

Querido E, Sfeir A, Chartrand P. Imaging of Telomerase RNA by Single-Molecule Inexpensive FISH Combined with Immunofluorescence. STAR Protoc. 2020 Sep 10;1(2):100104.

Sundqvist M, Holdfeldt A, Wright SC, Møller TC, Siaw E, Jennbacken K, Franzyk H, Bouvier M, Dahlgren C, Forsman H. Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis. Biochim Biophys Acta Mol Cell Res. 2020 Sep 8:118849.

Lewandowski JP, Dumbović G, Watson AR, Hwang T, Jacobs-Palmer E, Chang N, Much C, Turner KM, Kirby C, Rubinstein ND, Groff AF, Liapis SC, Gerhardinger C, Bester A, Pandolfi PP, Clohessy JG, Hoekstra HE, Sauvageau M, Rinn JL. The Tug1 lncRNA locus is essential for male fertility. Genome Biol. 2020 Sep 7;21(1):237.

Shao Z, Lee BJ, Rouleau-Turcotte É, Langelier MF, Lin X, Estes VM, Pascal JM, Zha S. Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo. Nucleic Acids Res. 2020 Sep 5:gkaa718. doi: 10.1093/nar/gkaa718.

Valach M, Alcazar JAG, Sarrasin M, Lang BF, Gray MW, Burger G. An unexpectedly complex mitoribosome in Andalucia godoyi, a protist with the most bacteria-like mitochondrial genome. Mol Biol Evol. 2020 Sep 4:msaa223. doi: 10.1093/molbev/msaa223.

Abe KT, Li Z, Samson R, Samavarchi-Tehrani P, Valcourt EJ, Wood H, Budylowski P, Dupuis Ii AP, Girardin RC, Rathod B, Wang J, Barrios-Rodiles M, Colwill K, McGeer A, Mubareka S, Gommerman JL, Durocher Y, Ostrowski M, McDonough KA, Drebot MA, Drews SJ, Rini JM, Gingras AC. A simple protein-based surrogate neutralization assay for SARS-CoV-2. JCI Insight. 2020 Sep 1:142362.

Beauséjour M, Vaillancourt F, Akoume MY, Franco A, Parent S, Labelle H, Joncas J, Desbiens-Blais F, Mac-Thiong JM, Roy-Beaudry M, Aubin CÉ, Moreau A. Patient outcomes in idiopathic scoliosis are associated with biological endophenotypes: 2020 SOSORT award winner. Eur Spine J. 2020 Aug 29. doi: 10.1007/s00586-020-06579-1.

Okashah N, Wright SC, Kawakami K, Mathiasen S, Zhou J, Lu S, Javitch JA, Inoue A, Bouvier M, Lambert NA. Agonist-induced formation of unproductive receptor-G12 complexes. Proc Natl Acad Sci U S A. 2020 Aug 17:202003787. doi: 10.1073/pnas.2003787117.

Dagenais P, Legault P. In Vitro Selection of Varkud Satellite Ribozyme Variants that Cleave a Modified Stem-Loop Substrate. Methods Mol Biol. 2021;2167:61-77.

Ghanbari F, Mader S, Philip A. Cholesterol as an Endogenous Ligand of ERRα Promotes ERRα-Mediated Cellular Proliferation and Metabolic Target Gene Expression in Breast Cancer Cells. Cells. 2020 Jul 23;9(8):E1765.

Koirala S, Klein J, Zheng Y, Glenn NO, Eisemann T, Fon Tacer K, Miller DJ, Kulak O, Lu M, Finkelstein DB, Neale G, Tillman H, Vogel P, Strand DW, Lum L, Brautigam CA, Pascal JM, Clements WK, Potts PR. Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase. Cell Rep. 2020 Jul 21;32(3):107922.

Cohen AA, Kennedy BK, Anglas U, Bronikowski AM, Deelen J, Dufour F, Ferbeyre G, Ferrucci L, Franceschi C, Frasca D, Friguet B, Gaudreau P, Gladyshev VN, Gonos ES, Gorbunova V, Gut P, Ivanchenko M, Legault V, Lemaître JF, Liontis T, Liu GH, Liu M, Maier AB, Nóbrega OT, Rikkert MGMO, Pawelec G, Rheault S, Senior AM, Simm A, Soo S, Traa A, Ukraintseva S, Vanhaelen Q, Van Raamsdonk JM, Witkowski JM, Yashin AI, Ziman R, Fülöp T. Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework. Mech Ageing Dev. 2020 Jul 18:111316. doi: 10.1016/j.mad.2020.111316.

Bottardi S, Guieze R, Bourgoin V, Fotouhi-Ardakani N, Dougé A, Darracq A, Lakehal YA, Berger MG, Mollica L, Bay JO, Omichinski JG, Milot E. MNDA controls the expression of MCL-1 and BCL-2 in chronic lymphocytic leukemia cells. Exp Hematol. 2020 Jul 16. pii: S0301-472X(20)30269-1.

Kamada R, Kudoh F, Ito S, Tani I, Janairo JIB, Omichinski JG, Sakaguchi K. Metal-dependent Ser/Thr protein phosphatase PPM family: Evolution, structures, diseases and inhibitors. Pharmacol Ther. 2020 Jul 7:107622.

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