Distinctions et publications

Publications 2021

Gaudreault J, Liberelle B, Durocher Y, Henry O, De Crescenzo G. Determination of the composition of heterogeneous binder solutions by surface plasmon resonance biosensing. Sci Rep. 2021 Feb 11;11(1):3685.

Jayabalan AK, Adivarahan S, Koppula A, Abraham R, Batish M, Zenklusen D, Griffin DE, Leung AKL. Stress granule formation, disassembly, and composition are regulated by alphavirus ADP-ribosylhydrolase activity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2021719118.

Tschaikner P, Regele D, Röck R, Salvenmoser W, Meyer D, Bouvier M, Geley S, Stefan E, Aanstad P. Feedback Control of the Gpr161-Gαs-PKA axis contributes to basal Hedgehog repression in zebrafish. Development. 2021 Feb 2:dev.192443.

Trân K, Van Den Hauwe R, Sainsily X, Couvineau P, Côté J, Simard L, Echevarria M, Murza A, Serre A, Théroux L, Saibi S, Haroune L, Longpré JM, Lesur O, Auger-Messier M, Spino C, Bouvier M, Sarret P, Ballet S, Marsault É. Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile. J Med Chem. 2021 Feb 1. doi: 10.1021/acs.jmedchem.0c01941.

Ogden TEH, Yang JC, Schimpl M, Easton LE, Underwood E, Rawlins PB, McCauley MM, Langelier MF, Pascal JM, Embrey KJ, Neuhaus D. Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition. Nucleic Acids Res. 2021 Jan 28:gkab020.

Stuible M, Gervais C, Lord-Dufour S, Perret S, L’Abbé D, Schrag J, St-Laurent G, Durocher Y. Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells. J Biotechnol. 2021 Jan 20;326:21-27.

Knüppel R, Trahan C, Kern M, Wagner A, Grünberger F, Hausner W, Quax TEF, Albers SV, Oeffinger M, Ferreira-Cerca S. Insights into synthesis and function of KsgA/Dim1-dependent rRNA modifications in archaea. Nucleic Acids Res. 2021 Jan 12:gkaa1268.

Hammel M, Rashid I, Sverzhinsky A, Pourfarjam Y, Tsai MS, Ellenberger T, Pascal JM, Kim IK, Tainer JA, Tomkinson AE. An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex. Nucleic Acids Res. 2021 Jan 11;49(1):306-321.

René P, Lanfray D, Richard D, Bouvier M. Pharmacological chaperone action in humanized mouse models of MC4R-linked obesity. JCI Insight. 2021 Jan 12:132778.

Van Nostrand EL, Freese P, Pratt GA, Wang X, Wei X, Xiao R, Blue SM, Chen JY, Cody NAL, Dominguez D, Olson S, Sundararaman B, Zhan L, Bazile C, Bouvrette LPB, Bergalet J, Duff MO, Garcia KE, Gelboin-Burkhart C, Hochman M, Lambert NJ, Li H, McGurk MP, Nguyen TB, Palden T, Rabano I, Sathe S, Stanton R, Su A, Wang R, Yee BA, Zhou B, Louie AL, Aigner S, Fu XD, Lécuyer E, Burge CB, Graveley BR, Yeo GW. A large-scale binding and functional map of human RNA-binding proteins. Nature. 2021 Jan 5. doi: 10.1038/s41586-020-03067-w.

Adivarahan S, Zenklusen D. Probing the Conformational State of mRNPs Using smFISH and SIM. Methods Mol Biol. 2021; 2209:267-286.

Publications 2020

Genois MM, Gagné JP, Yasuhara T, Jackson J, Saxena S, Langelier MF, Ahel I, Bedford MT, Pascal JM, Vindigni A, Poirier GG, Zou L. CARM1 regulates replication fork speed and stress response by stimulating PARP1. Mol Cell. 2020 Dec 30:S1097-2765(20)30902-3.

Trân K, Murza A, Sainsily X, Delile E, Couvineau P, Côté J, Coquerel D, Peloquin M, Auger-Messier M, Bouvier M, Lesur O, Sarret P, Marsault É. Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor. J Med Chem. 2020 Dec 22. doi: 10.1021/acs.jmedchem.0c01547.

Simões SC, Balico-Silva AL, Parreiras-E-Silva LT, Bitencourt ALB, Bouvier M, Costa-Neto CM. Signal Transduction Profiling of Angiotensin II Type 1 Receptor With Mutations Associated to Atrial Fibrillation in Humans. Front Pharmacol. 2020 Dec 22;11:600132.

Hammel M, Rashid I, Sverzhinsky A, Pourfarjam Y, Tsai MS, Ellenberger T, Pascal JM, Kim IK, Tainer JA, Tomkinson AE. An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex. Nucleic Acids Res. 2020 Dec 16:gkaa1188.

Corrêa MF, Balico-Silva AL, Kiss DJ, Fernandes GAB, Maraschin JC, Parreiras-E-Silva LT, Varela MT, Simões SC, Bouvier M, Keserű GM, Costa-Neto CM, Fernandes JPS.  Novel potent (dihydro)benzofuranyl piperazines as human histamine receptor ligands – Functional characterization and modeling studies on H3 and H4 receptors. Bioorg Med Chem. 2020 Dec 8;30:115924.

Latorraca NR, Masureel M, Hollingsworth SA, Heydenreich FM, Suomivuori CM, Brinton C, Townshend RJL, Bouvier M, Kobilka BK, Dror RO. How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling. Cell. 2020 Dec 8:S0092-8674(20)31531-2.

Serrano D, Cordero G, Kawamura R, Sverzhinsky A, Sarker M, Roy S, Malo C, Pascal JM, Marko JF, D’Amours D. The Smc5/6 Core Complex Is a Structure-Specific DNA Binding and Compacting Machine. Mol Cell. 2020 Dec 7:S1097-2765(20)30789-9.

Stuible M, Gervais C, Lord-Dufour S, Perret S, L’Abbé D, Schrag J, St-Laurent G, Durocher Y. Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells. J Biotechnol. 2020 Dec 7:S0168-1656(20)30327-8.

Moiseeva O, Guillon J, Ferbeyre G. Senescence: a program in the road to cell elimination and cancer. Semin Cancer Biol. 2020 Dec 23:S1044-579X(20)30277-7.

Avet C, Sturino C, Grastilleur S, Gouill CL, Semache M, Gross F, Gendron L, Bennani Y, Mancini JA, Sayegh CE, Bouvier M. The PAR2 inhibitor I-287 selectively targets Gαq and Gα12/13 signaling and has anti-inflammatory effects. Commun Biol. 2020 Nov 27;3(1):719.

Rouleau-Turcotte É, Pascal JM. Bridging a DNA Break to Leave a Poly(ADP-Ribose) Mark on Chromatin. Mol Cell. 2020 Nov 19;80(4):560-561.

Dodat F, Cotnoir-White D, Dianati E, Vallet A, Mader S, Lévesque D. Complex regulation of orphan nuclear receptor Nur77 (Nr4a1) transcriptional activity by SUMO2 and PIASγ. Biochim Biophys Acta Mol Cell Res. 2020 Nov 12:118908.

Nepotchatykh E, Elremaly W, Caraus I, Godbout C, Leveau C, Chalder L, Beaudin C, Kanamaru E, Kosovskaia R, Lauzon S, Maillet Y, Franco A, Lascau-Coman V, Bouhanik S, Gaitan YP, Li D, Moreau A. Profile of circulating microRNAs in myalgic encephalomyelitis and their relation to symptom severity, and disease pathophysiology. Sci Rep. 2020 Nov 12;10(1):19620.

Natalia Zamorano Cuervo , Nathalie Grandvaux. ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities. Elife. 2020 Nov 9;9:e61390.

Matsumoto Y, Brooks RC, Sverzhinsky A, Pascal JM, Tomkinson AE. Dynamic DNA-bound PCNA complexes co-ordinate Okazaki fragment synthesis, processing and ligation. J Mol Biol. 2020 Nov 3:S0022-2836(20)30616-1.

Aguilar LC, Paul B, Reiter T, Gendron L, Arul Nambi Rajan A, Montpetit R, Trahan C, Pechmann S, Oeffinger M, Montpetit B. Altered rRNA processing disrupts nuclear RNA homeostasis via competition for the poly(A)-binding protein Nab2. Nucleic Acids Res. 2020 Nov 2:gkaa964.

Garrido D, Bourouh M, Bonneil É, Thibault P, Swan A, Archambault V. Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis. PLoS Genet. 2020 Nov 2;16(11):e1009184.

Møller TC, Pedersen MF, van Senten JR, Seiersen SD, Mathiesen JM, Bouvier M, Bräuner-Osborne H. Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells. Sci Rep. 2020 Oct 15;10(1):17395.

Imam A, Winnebeck EC, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study. Front Physiol. 2020 Oct 9;11:564140.

Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras AC. Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. Sci Immunol. 2020 Oct 8;5(52):eabe5511.

Abe KT, Li Z, Samson R, Samavarchi-Tehrani P, Valcourt EJ, Wood H, Budylowski P, Dupuis AP 2nd, Girardin RC, Rathod B, Wang JH, Barrios-Rodiles M, Colwill K, McGeer AJ, Mubareka S, Gommerman JL, Durocher Y, Ostrowski M, McDonough KA, Drebot MA, Drews SJ, Rini JM, Gingras AC. A simple protein-based surrogate neutralization assay for SARS-CoV-2. JCI Insight. 2020 Oct 2;5(19):142362.

Quattrocchi V, Bidart J, Mignaqui AC, Ruiz V, Ferella A, Langellotti C, Gammella M, Ferraris S, Carrillo J, Wigdorovitz A, Durocher Y, Cardillo SB, Charleston B, Zamorano PI. Bovine Dendritic Cell Activation, T Cell Proliferation and Antibody Responses to Foot-And-Mouth Disease, Is Similar With Inactivated Virus and Virus Like Particles. Front Vet Sci. 2020 Sep 30;7:594.

Chin A, Lécuyer E. Translating Messages in Different Neighborhoods. Dev Cell. 2020 Sep 28;54(6):691-693.

Smith M, Querido E, Chartrand P, Sfeir A. Quantitative Imaging of MS2-Tagged hTR in Cajal Bodies: Photobleaching and Photoactivation. STAR Protoc. 2020 Sep 24;1(3):100112.

Mignaqui AC, Ferella A, Cass B, Mukankurayija L, L’Abbé D, Bisson L, Sánchez C, Scian R, Cardillo SB, Durocher Y, Wigdorovitz A. Foot-and-Mouth Disease: Optimization, Reproducibility, and Scalability of High-Yield Production of Virus-Like Particles for a Next-Generation Vaccine. Front Vet Sci. 2020 Sep 23;7:601.

Chartrand P, Sfeir A. A single-molecule view of telomerase regulation at telomeres. Mol Cell Oncol. 2020 Sep 20;7(6):1818537.

Fabre L, Ntreh AT, Yazidi A, Leus IV, Weeks JW, Bhattacharyya S, Ruickoldt J, Rouiller I, Zgurskaya HI, Sygusch J. A « Drug Sweeping » State of the TriABC Triclosan Efflux Pump from Pseudomonas aeruginosa. Structure. 2020 Sep 15:S0969-2126(20)30326-9.

Kouwenhoven WM, Fortin G, Penttinen AM, Florence C, Delignat-Lavaud B, Bourque MJ, Trimbuch T, Luppi MP, Salvail-Lacoste A, Legault P, Poulin JF, Rosenmund C, Awatramani R, Trudeau LÉ. VGLUT2 EXPRESSION IN DOPAMINE NEURONS CONTRIBUTES TO POST-LESIONAL STRIATAL REINNERVATION. J Neurosci. 2020 Sep 14:JN-RM-0823-20.

Querido E, Sfeir A, Chartrand P. Imaging of Telomerase RNA by Single-Molecule Inexpensive FISH Combined with Immunofluorescence. STAR Protoc. 2020 Sep 10;1(2):100104.

Sundqvist M, Holdfeldt A, Wright SC, Møller TC, Siaw E, Jennbacken K, Franzyk H, Bouvier M, Dahlgren C, Forsman H. Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis. Biochim Biophys Acta Mol Cell Res. 2020 Sep 8:118849.

Lewandowski JP, Dumbović G, Watson AR, Hwang T, Jacobs-Palmer E, Chang N, Much C, Turner KM, Kirby C, Rubinstein ND, Groff AF, Liapis SC, Gerhardinger C, Bester A, Pandolfi PP, Clohessy JG, Hoekstra HE, Sauvageau M, Rinn JL. The Tug1 lncRNA locus is essential for male fertility. Genome Biol. 2020 Sep 7;21(1):237.

Shao Z, Lee BJ, Rouleau-Turcotte É, Langelier MF, Lin X, Estes VM, Pascal JM, Zha S. Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo. Nucleic Acids Res. 2020 Sep 5:gkaa718. doi: 10.1093/nar/gkaa718.

Valach M, Alcazar JAG, Sarrasin M, Lang BF, Gray MW, Burger G. An unexpectedly complex mitoribosome in Andalucia godoyi, a protist with the most bacteria-like mitochondrial genome. Mol Biol Evol. 2020 Sep 4:msaa223. doi: 10.1093/molbev/msaa223.

Abe KT, Li Z, Samson R, Samavarchi-Tehrani P, Valcourt EJ, Wood H, Budylowski P, Dupuis Ii AP, Girardin RC, Rathod B, Wang J, Barrios-Rodiles M, Colwill K, McGeer A, Mubareka S, Gommerman JL, Durocher Y, Ostrowski M, McDonough KA, Drebot MA, Drews SJ, Rini JM, Gingras AC. A simple protein-based surrogate neutralization assay for SARS-CoV-2. JCI Insight. 2020 Sep 1:142362.

Beauséjour M, Vaillancourt F, Akoume MY, Franco A, Parent S, Labelle H, Joncas J, Desbiens-Blais F, Mac-Thiong JM, Roy-Beaudry M, Aubin CÉ, Moreau A. Patient outcomes in idiopathic scoliosis are associated with biological endophenotypes: 2020 SOSORT award winner. Eur Spine J. 2020 Aug 29. doi: 10.1007/s00586-020-06579-1.

Okashah N, Wright SC, Kawakami K, Mathiasen S, Zhou J, Lu S, Javitch JA, Inoue A, Bouvier M, Lambert NA. Agonist-induced formation of unproductive receptor-G12 complexes. Proc Natl Acad Sci U S A. 2020 Aug 17:202003787. doi: 10.1073/pnas.2003787117.

Dagenais P, Legault P. In Vitro Selection of Varkud Satellite Ribozyme Variants that Cleave a Modified Stem-Loop Substrate. Methods Mol Biol. 2021;2167:61-77.

Ghanbari F, Mader S, Philip A. Cholesterol as an Endogenous Ligand of ERRα Promotes ERRα-Mediated Cellular Proliferation and Metabolic Target Gene Expression in Breast Cancer Cells. Cells. 2020 Jul 23;9(8):E1765.

Koirala S, Klein J, Zheng Y, Glenn NO, Eisemann T, Fon Tacer K, Miller DJ, Kulak O, Lu M, Finkelstein DB, Neale G, Tillman H, Vogel P, Strand DW, Lum L, Brautigam CA, Pascal JM, Clements WK, Potts PR. Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase. Cell Rep. 2020 Jul 21;32(3):107922.

Cohen AA, Kennedy BK, Anglas U, Bronikowski AM, Deelen J, Dufour F, Ferbeyre G, Ferrucci L, Franceschi C, Frasca D, Friguet B, Gaudreau P, Gladyshev VN, Gonos ES, Gorbunova V, Gut P, Ivanchenko M, Legault V, Lemaître JF, Liontis T, Liu GH, Liu M, Maier AB, Nóbrega OT, Rikkert MGMO, Pawelec G, Rheault S, Senior AM, Simm A, Soo S, Traa A, Ukraintseva S, Vanhaelen Q, Van Raamsdonk JM, Witkowski JM, Yashin AI, Ziman R, Fülöp T. Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework. Mech Ageing Dev. 2020 Jul 18:111316. doi: 10.1016/j.mad.2020.111316.

Bottardi S, Guieze R, Bourgoin V, Fotouhi-Ardakani N, Dougé A, Darracq A, Lakehal YA, Berger MG, Mollica L, Bay JO, Omichinski JG, Milot E. MNDA controls the expression of MCL-1 and BCL-2 in chronic lymphocytic leukemia cells. Exp Hematol. 2020 Jul 16. pii: S0301-472X(20)30269-1.

Kamada R, Kudoh F, Ito S, Tani I, Janairo JIB, Omichinski JG, Sakaguchi K. Metal-dependent Ser/Thr protein phosphatase PPM family: Evolution, structures, diseases and inhibitors. Pharmacol Ther. 2020 Jul 7:107622.

ENCODE Project Consortium, Moore JE, Purcaro MJ, Pratt HE, Epstein CB, Shoresh N, Adrian J, Kawli T, Davis CA, Dobin A, Kaul R, Halow J, Van Nostrand EL, Freese P, Gorkin DU, Shen Y, He Y, Mackiewicz M, Pauli-Behn F, Williams BA, Mortazavi A, Keller CA, Zhang XO, Elhajjajy SI, Huey J, Dickel DE, Snetkova V, Wei X, Wang X, Rivera-Mulia JC, Rozowsky J, Zhang J, Chhetri SB, Zhang J, Victorsen A, White KP, Visel A, Yeo GW, Burge CB, Lécuyer E, Gilbert DM, Dekker J, Rinn J, Mendenhall EM, Ecker JR, Kellis M, Klein RJ, Noble WS, Kundaje A, Guigó R, Farnham PJ, Cherry JM, Myers RM, Ren B, Graveley BR, Gerstein MB, Pennacchio LA, Snyder MP, Bernstein BE, Wold B, Hardison RC, Gingeras TR, Stamatoyannopoulos JA, Weng Z. Expanded encyclopaedias of DNA elements in the human and mouse genomes. Nature. 2020 Jul;583(7818):699-710.

Hassine S, Bonnet-Magnaval F, Benoit Bouvrette LP, Doran B, Ghram M, Bouthillette M, Lecuyer E, DesGroseillers L. Staufen1 localizes to the mitotic spindle and controls the localization of RNA populations to the spindle. J Cell Sci. 2020 Jun 23. pii: jcs.247155. doi: 10.1242/jcs.247155.

Faktorová D, Kaur B, Valach M, Graf L, Benz C, Burger G, Lukeš J. Targeted integration by homologous recombination enables in-situ tagging and replacement of genes in the marine microeukaryote Diplonema papillatum. Environ Microbiol. 2020 Jun 16. doi: 10.1111/1462-2920.15130.

Laprade H, Querido E, Smith MJ, Guérit D, Crimmins H, Conomos D, Pourret E, Chartrand P, Sfeir A. Single-Molecule Imaging of Telomerase RNA Reveals a Recruitment-Retention Model for Telomere Elongation. Mol Cell. 2020 May 29. pii: S1097-2765(20)30306-3.

Lukasheva V, Devost D, Le Gouill C, Namkung Y, Martin RD, Longpré JM, Amraei M, Shinjo Y, Hogue M, Lagacé M, Breton B, Aoki J, Tanny JC, Laporte SA, Pineyro G, Inoue A, Bouvier M, Hébert TE. Signal profiling of the β1AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β1AR and β2AR. Sci Rep. 2020 May 29;10(1):8779.

Srirangan K, Loignon M, Durocher Y. The use of site-specific recombination and cassette exchange technologies for monoclonal antibody production in Chinese Hamster ovary cells: retrospective analysis and future directions. Crit Rev Biotechnol. 2020 May 26:1-19. doi: 10.1080/07388551.

Baidya M, Kumari P, Dwivedi-Agnihotri H, Pandey S, Sokrat B, Sposini S, Chaturvedi M, Srivastava A, Roy D, Hanyaloglu AC, Bouvier M, Shukla AK. Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G protein-coupled receptors. J Biol Chem. 2020 May 21. pii: jbc.RA120.013470.

Nourreddine S, Lavoie G, Paradis J, Ben El Kadhi K, Méant A, Aubert L, Grondin B, Gendron P, Chabot B, Bouvier M, Carreno S, Roux PP.     NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay. Cell Rep. 2020 May 19;31(7):107660.

Chartrand P, Jaramillo M, Gamberi C. Editorial: RNA Regulation in Development and Disease. Front Genet. 2020 Apr 28;11:430. doi: 10.3389/fgene.2020.00430.

Ghram M, Bonnet-Magnaval F, Hotea DI, Doran B, Ly S, DesGroseillers L. Staufen1 is essential for cell cycle transitions and cell proliferation via the control of E2F1 expression. J Mol Biol. 2020 Apr 23. pii: S0022-2836(20)30304-1.

Lussier-Price M, Mascle XH, Cappadocia L, Kamada R, Sakaguchi K, Wahba HM, Omichinski JG. Characterization of a C-Terminal SUMO-Interacting Motif Present in Select PIAS-Family Proteins. Structure. 2020 Apr 22. pii: S0969-2126(20)30121-0.

Rahim MMA,  Parsons BD,  Price EL,  Slaine PD,  Chilvers BL,  Seaton GS,  Wight A,  Medina-Luna D,  Dey S,  Grandy SL,  Anderson LE,  Zamorano Cuervo N,  Grandvaux N,  Gaglia MM,  Kelvin AA,  Khaperskyy DA,  McCormick C,  Makrigiannis AP. Defective influenza A virus RNA products mediate MAVS-dependent upregulation of human leukocyte antigen class I proteins. J Virol. 2020 Jun 16;94(13):e00165-20.

 Faktorová D, Nisbet RER, Fernández Robledo JA, Casacuberta E, Sudek L, Allen AE, Ares M Jr, Aresté C, Balestreri C, Barbrook AC, Beardslee P, Bender S, Booth DS, Bouget FY, Bowler C, Breglia SA, Brownlee C, Burger G, Cerutti H,Cesaroni R, Chiurillo MA, Clemente T, Coles DB, Collier JL, Cooney EC, Coyne K, Docampo R, Dupont CL, Edgcomb V, Einarsson E, Elustondo PA, Federici F, Freire-Beneitez V, Freyria NJ, Fukuda K, García PA, Girguis PR, Gomaa F, Gornik SG, Guo J, Hampl V, HanawaY, Haro-Contreras ER, Hehenberger E, Highfield A, Hirakawa Y, Hopes A, Howe CJ, Hu I, Ibañez J, Irwin NAT, Ishii Y, Janowicz NE, Jones AC, Kachale A, Fujimura-Kamada K, Kaur B, Kaye JZ, Kazana E, Keeling PJ, King N, Klobutcher LA, Lander N, Lassadi I, Li Z,Lin S, Lozano JC, Luan F, Maruyama S, Matute T, Miceli C, Minagawa J, Moosburner M, Najle SR, Nanjappa D, Nimmo IC, Noble L, Novák Vanclová AMG, Nowacki M, Nuñez I, Pain A, Piersanti A, Pucciarelli S, Pyrih J, Rest JS, Rius M, Robertson D, Ruaud A, Ruiz-TrilloI, Sigg MA, Silver PA, Slamovits CH, Jason Smith G, Sprecher BN, Stern R, Swart EC, Tsaousis AD, Tsypin L, Turkewitz A, Turnšek J, Valach M, Vergé V, von Dassow P, von der Haar T, Waller RF, Wang L, Wen X, Wheeler G, Woods A, Zhang H, Mock T, Worden AZ, Lukeš J. Genetic tool development in marine protists: emerging model organisms for experimental cell biology. Nat Methods. 2020 Apr 6. doi: 10.1038/s41592-020-0796-x.

Zandarashvili L, Langelier MF, Velagapudi UK, Hancock MA, Steffen JD, Billur R, Hannan ZM, Wicks AJ, Krastev DB, Pettitt SJ, Lord CJ, Talele TT, Pascal JM, Black BE. Structural basis for allosteric PARP-1 retention on DNA breaks. Science. 2020 Apr 3;368(6486).

Cambay F, Forest-Nault C, Dumoulin L, Seguin A, Henry O, Durocher Y, De Crescenzo G. Glycosylation of Fcγ receptors influences their interaction with various IgG1 glycoforms. Mol Immunol. 2020 Mar 26;121:144-158.

Camacho D, Frazao R, Fouillen A, Nanci A, Lang BF, Apte SC, Baron C, Warren LA. New Insights Into Acidithiobacillus thiooxidans Sulfur Metabolism Through Coupled Gene Expression, Solution Chemistry, Microscopy, and Spectroscopy Analyses. Front Microbiol. 2020 Mar 13;11:411.

Bergalet J, Patel D, Legendre F, Lapointe C, Benoit Bouvrette LP, Chin A, Blanchette M, Kwon E, Lécuyer E. Inter-dependent Centrosomal Co-localization of the cen and ik2 cis-Natural Antisense mRNAs in Drosophila. Cell Rep. 2020 Mar 10;30(10):3339-3352.

Gray MW, Burger G, Derelle R, Klimeš V, Leger MM, Sarrasin M, Vlček Č, Roger AJ, Eliáš M, Lang BF. The draft nuclear genome sequence and predicted mitochondrial proteome of Andalucia godoyi, a protist with the most gene-rich and bacteria-like mitochondrial genome. BMC Biol. 2020 Mar 2;18(1):22. doi: 10.1186/s12915-020-0741-6.

Manenda MS, Picard MÈ, Zhang L, Cyr N, Zhu X, Barma J, Pascal JM, Couture M, Zhang C, Shi R. Structural analyses of the group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations. J Biol Chem. 2020 Feb 28. pii: jbc.RA119.011212.

Jasinska W, Manhart M, Lerner J, Gauthier L, Serohijos AWR, Bershtein S. Chromosomal barcoding of E. coli populations reveals lineage diversity dynamics at high resolution. Nat Ecol Evol. 2020 Feb 24. doi: 10.1038/s41559-020-1103-z.

Lalonde M, Chartrand P. TERRA, a multifaceted regulator of telomerase activity at telomeres. J Mol Biol. 2020 Feb 18. pii: S0022-2836(20)30154-6.

Alexander RA, Lot I, Saha K, Abadie G, Lambert M, Decosta E, Kobayashi H, Beautrait A, Borrull A, Asnacios A, Bouvier M, Scott MGH, Marullo S, Enslen H. Beta-arrestins operate an on/off control switch for focal adhesion kinase activity. Cell Mol Life Sci. 2020 Feb 10. doi: 10.1007/s00018-020-03471-5.

Semmler S, Gagné M, Garg P, Pickles SR , Baudouin C, Hamon-Keromen E, Destroismaisons L, Khalfallah Y, Chaineau M, Caron E , Bayne AN, Trempe JF, Cashman NR, Star AT, Haqqani AS, Durcan TM, Meiering EM, Robertson J, Grandvaux N, Plotkin SS, McBride HM, Vande Velde C. TNF receptor associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation. J Biol Chem. 2020 Feb 6. pii: jbc.RA119.011215.

Nakagawa N, Sakaguchi S, Nomura T, Kamada R, Omichinski JG, Sakaguchi K. The tetramerization domain of the tree shrew p53 protein displays unique thermostability despite sharing high sequence identity with the human p53 protein. Biochem Biophys Res Commun. 2020 Jan 15;521(3):681-686.

Kaur B, Záhonová K, Valach M, Faktorová D, Prokopchuk G, Burger G, Lukeš J. Gene fragmentation and RNA editing without borders: eccentric mitochondrial genomes of diplonemids. Nucleic Acids Res. 2020 Jan 10. pii: gkz1215. doi: 10.1093/nar/gkz1215.

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