{"id":1723,"date":"2012-07-19T10:40:33","date_gmt":"2012-07-19T09:40:33","guid":{"rendered":"http:\/\/biochimie.umontreal.ca\/?page_id=1723"},"modified":"2016-10-12T15:45:16","modified_gmt":"2016-10-12T19:45:16","slug":"martine-raymond","status":"publish","type":"page","link":"https:\/\/biochimie.umontreal.ca\/en\/department\/martine-raymond\/","title":{"rendered":"Martine Raymond"},"content":{"rendered":"

Professor<\/h2>\n\n\n\n
\"\"<\/td>\n\n

Contact Information<\/h2>\n

Institut de Recherche en Immunologie et Canc\u00e9rologie
\nUniversit\u00e9 de Montr\u00e9al
\nPavillon Marcelle-Coutu, bureau 3306-17
\nC.P. 6128, Succ. Centre-ville
\nMontr\u00e9al (Qu\u00e9bec)
\nH3C 3J7<\/td>\n

\n

.<\/span><\/h2>\n

P<\/strong> 514 343-6746
\nF<\/strong> 514 343-6843
\nmartine.raymond@umontreal.ca<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n
\n

Themes<\/h3>\n
    \n
  • Yeast Molecular Biology<\/li>\n
  • Genetics and Functional Genomics<\/li>\n
  • Multidrug Resistance<\/li>\n
  • Cellular Target and Antifungal Drug Discovery<\/li>\n<\/ul>\n

    Our research focuses on the molecular biology of Candida albicans, an opportunistic yeast that causes systemic or mucosal infections in immunocompromised individuals (such as HIV patients, patients undergoing chemotherapy or organ transplant).\u00a0 Our laboratory uses genetic, genomic and molecular biology approaches to understand the mechanisms responsible for C. albicans multidrug resistance and virulence.\u00a0 In particular, we are interested in understanding the function of multidrug transporters of the ATP-binding cassette family which export antifungal drugs out of the cells.\u00a0 Using functional genomics (DNA microarrays), we work at identifying the transcriptional networks controlling multidrug resistance and virulence in C. albicans.\u00a0 Finally, our laboratory is part of a CIHR multidisciplinary team on fungal pathogenesis grouping several Montreal-based researchers whose objective is to discover new C. albicans target proteins or small non-coding RNAs for antifungal drug development.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    Publications<\/h3>\n
      \n
    • Znaidi, S., Weber, S. Zin Al-Abdin, O., Bomme, P., Saidane, S., Drouin, S., Lemieux, S., De Deken, X., Robert, F. and Raymond, M.\u00a0 2008.\u00a0 Genome-wide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance.\u00a0 Eukaryotic Cell. 7:836-847.<\/li>\n
    • Liu, T.T., Znaidi, S., Barker, K.S., Xu, L., Homayouni, R., Saidane, S., Morschh\u00e4user, J., Nantel, A., Raymond, M., and Rogers, P.D.\u00a0 2007.\u00a0 Genome-wide expression and location analyses of the Candida albicans Tac1p regulon.\u00a0 Eukaryotic Cell. 6:2122-2138.<\/li>\n
    • Znaidi, S., De Deken, X., Weber, S., Rigby, T., Nantel, A. and Raymond, M.\u00a0 2007.\u00a0 The zinc finger transcription factor Tac1p regulates PDR16 expression in Candida albicans.\u00a0 Mol. Microbiol. 66:440-452.<\/li>\n
    • Saidane, S., Weber, S., De Deken, X., St-Germain, G., and Raymond, M.\u00a0 2006.\u00a0 PDR16-mediated clinical azole resistance in Candida albicans.Mol. Microbiol. 60:1546-1562.<\/li>\n
    • Gauthier, C., Weber, S., Alarco, A.-M., Alqawi, O., Daoud, R., Georges, E. and Raymond, M. 2003. Functional similarities and differences between the Candida albicans Cdr1p and Cdr2p transporters.\u00a0 Antimicrob. Agents Chemother. 47:1543-1554.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

      Professor Contact Information Institut de Recherche en Immunologie et Canc\u00e9rologie Universit\u00e9 de Montr\u00e9al Pavillon Marcelle-Coutu, bureau 3306-17 C.P. 6128, Succ. Centre-ville Montr\u00e9al (Qu\u00e9bec) H3C 3J7 . P 514 343-6746 F […]<\/p>\n","protected":false},"author":25,"featured_media":0,"parent":11439,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1723","page","type-page","status-publish","hentry"],"yoast_head":"\nMartine Raymond - D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/biochimie.umontreal.ca\/en\/department\/martine-raymond\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Martine Raymond - D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire\" \/>\n<meta property=\"og:description\" content=\"Professor Contact Information Institut de Recherche en Immunologie et Canc\u00e9rologie Universit\u00e9 de Montr\u00e9al Pavillon Marcelle-Coutu, bureau 3306-17 C.P. 6128, Succ. 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