{"id":1692,"date":"2012-07-18T15:25:06","date_gmt":"2012-07-18T14:25:06","guid":{"rendered":"http:\/\/biochimie.umontreal.ca\/?page_id=1692"},"modified":"2016-10-12T15:45:16","modified_gmt":"2016-10-12T19:45:16","slug":"james-g-omichinski","status":"publish","type":"page","link":"https:\/\/biochimie.umontreal.ca\/en\/department\/james-g-omichinski\/","title":{"rendered":"James G. Omichinski"},"content":{"rendered":"<h2>Professor<\/h2>\n<table>\n<tbody>\n<tr>\n<td style=\"vertical-align: middle\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-1693\" title=\"jim_omichinski\" src=\"https:\/\/biochimie.umontreal.ca\/wp-content\/uploads\/sites\/37\/2012\/07\/jim_omichinski.jpg\" alt=\"\" height=\"121\" width=\"120\" \/><\/td>\n<td style=\"vertical-align: top\">\n<h2>Contact Information<\/h2>\n<p>D\u00e9partement de biochimie<br \/>\nFacult\u00e9 de m\u00e9decine<br \/>\nUniversit\u00e9 de Montr\u00e9al<br \/>\nPavillon Roger-Gaudry, room D-301<br \/>\nC.P. 6128, Succ. Centre-ville<br \/>\nMontr\u00e9al (Qu\u00e9bec)<br \/>\nH3C 3J7<\/td>\n<td style=\"vertical-align: top\">\n<h2><span style=\"color: #ffffff\">.<\/span><\/h2>\n<p><strong>P<\/strong> 514 343-6111 ext. 7341<br \/>\n<strong>F<\/strong> 514 343-2210<br \/>\n<a href=\"mailto:jg.omichinski@umontreal.ca\">jg.omichinski@umontreal.ca<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table>\n<tbody>\n<tr>\n<td>\n<h3>Themes<\/h3>\n<ul>\n<li>Structural analysis of macromolecules<\/li>\n<li>Developmental biology, Senescence and Cancer<\/li>\n<li>Control of gene expression<\/li>\n<\/ul>\n<p>NMR three-dimensional structure determination of DNA-protein complexes; systems involved in regulation of transcription, viral infections (HIV), cancer and development of new therapeutic agents.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Publications<\/h3>\n<ul>\n<li>Di Lello P, Miller Jenkins LM, Mas C, Langlois C, Malitskaya E, Fradet-Turcotte A, Archambault J, Legault P, Omichinski JG. (2008) p53 and TFIIEalpha share a common binding site on the Tfb1\/p62 subunit of TFIIH. Proc Natl Acad Sci USA. 105:106-11.<\/li>\n<li>Omichinski JG. 2007 Toward methylmercury bioremediation. Science 317:205-6.<\/li>\n<li>Jenkins LM, Durell SR, Maynard AT, Stahl SJ, Inman JK, Appella E, Legault P, Omichinski JG. (2006) Comparison of the specificity of interaction of cellular and viral zinc-binding domains with 2-mercaptobenzamide thioesters. J Am Chem Soc. 128:11964-76.<\/li>\n<li>Di Lello P, Jenkins LM, Jones TN, Nguyen BD, Hara T, Yamaguchi H, Dikeakos JD, Appella E, Legault P, Omichinski JG. (2006) Structure of the Tfb1\/p53 complex: Insights into the interaction between the p62\/Tfb1 subunit of TFIIH and the activation domain of p53. Mol Cell. 22 :731-40.<\/li>\n<li>Di Lello P, Nguyen BD, Jones TN, Potempa K, Kobor MS, Legault P, Omichinski JG. (2005) NMR structure of the amino-terminal domain from the Tfb1 subunit of TFIIH and characterization of its phosphoinositide and VP16 binding sites. Biochemistry. 44:7678-86.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Professor Contact Information D\u00e9partement de biochimie Facult\u00e9 de m\u00e9decine Universit\u00e9 de Montr\u00e9al Pavillon Roger-Gaudry, room D-301 C.P. 6128, Succ. Centre-ville Montr\u00e9al (Qu\u00e9bec) H3C 3J7 . P 514 343-6111 ext. 7341 [&hellip;]<\/p>\n","protected":false},"author":25,"featured_media":0,"parent":11439,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1692","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>James G. 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