{"id":1116,"date":"2012-06-26T15:51:18","date_gmt":"2012-06-26T14:51:18","guid":{"rendered":"http:\/\/biochimie.umontreal.ca\/?page_id=1116"},"modified":"2016-10-12T15:45:15","modified_gmt":"2016-10-12T19:45:15","slug":"gerardo-ferbeyre","status":"publish","type":"page","link":"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/","title":{"rendered":"Gerardo Ferbeyre"},"content":{"rendered":"

Professor<\/h2>\n\n\n\n
\"Gerry2015\"<\/td>\n\n

Contact information<\/h2>\n

D\u00e9partement de biochimie
\nFacult\u00e9 de M\u00e9decine
\nUniversit\u00e9 de Montr\u00e9al
\nPavillon Roger-Gaudry, room E-515
\nC.P. 6128, Succ. Centre-ville
\nMontr\u00e9al (Qu\u00e9bec)
\nH3C 3J7<\/td>\n

\n

.<\/span><\/h2>\n

P <\/strong>514 343-7571
\nF<\/strong> 514 343-2210
\ng.ferbeyre@umontreal.ca<\/a>
\nWWW<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n
\n

Themes<\/h3>\n
    \n
  • Developmental biology, Senescence and Cancer<\/li>\n
  • Gene expression control<\/li>\n
  • Cell signaling<\/li>\n<\/ul>\n

    My laboratory is interested in uncovering the molecular mechanism of tumor suppression. These mechanisms involve sensors that detect oncogenic stress and effector pathways that prevent the proliferative expansion of potentially malignant cells. Our work on senescence is leading us towards new mechanism of triggering anti-tumor immune response. We thus view cell senescence, not only as a way to stop the proliferation of incipient tumors but also as a mechanism to alert the immune system of a tumor threat and developing lasting antitumor immunity. Using proteomics, RNA interference and CRISPR screening we have identified many genes with unsuspected roles in tumor suppression and cellular senescence. Many of the genes can potentially regulate the immune system.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    Publications<\/h3>\n
      \n
    • Moiseeva O, Lessard F, Acevedo-Aquino M, Vernier M, Tsantrizos YS, Ferbeyre<\/strong> G. Mutant lamin A links prophase to a p53 independent senescence program. Cell Cycle<\/em>.<\/em> 2015 Aug 3;14(15):2408-2421.<\/li>\n
    • Desch\u00eanes-Simard, X., Gaumont-Leclerc, M.F., Bourdeau, V., Moiseeva, O., Forest, V., Ingelman, S., Mallette, F.A., Lessard, F., El-Leil, M.S., Meloche, S., Saad, F., Mes-Masson A.M. and Ferbeyre G.<\/strong> (2013). Tumor suppressor activity of the ERK\/MAPK pathway by promoting selective protein degradation. Genes and Dev<\/em> 27(8):900-15.<\/li>\n
    • Vernier M, Bourdeau V, Gaumont-Leclerc MF, Moiseeva O, B\u00e9gin V, Saad F, Mes-Masson AM, Ferbeyre G.<\/strong> (2011). Regulation of E2Fs and senescence by PML nuclear bodies. Genes Dev.<\/em> 25(1):41-50.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

      Professor Contact information D\u00e9partement de biochimie Facult\u00e9 de M\u00e9decine Universit\u00e9 de Montr\u00e9al Pavillon Roger-Gaudry, room E-515 C.P. 6128, Succ. Centre-ville Montr\u00e9al (Qu\u00e9bec) H3C 3J7 . P 514 343-7571 F 514 […]<\/p>\n","protected":false},"author":25,"featured_media":0,"parent":11439,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1116","page","type-page","status-publish","hentry"],"yoast_head":"\nGerardo Ferbeyre - D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Gerardo Ferbeyre - D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire\" \/>\n<meta property=\"og:description\" content=\"Professor Contact information D\u00e9partement de biochimie Facult\u00e9 de M\u00e9decine Universit\u00e9 de Montr\u00e9al Pavillon Roger-Gaudry, room E-515 C.P. 6128, Succ. Centre-ville Montr\u00e9al (Qu\u00e9bec) H3C 3J7 . P 514 343-7571 F 514 […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/\" \/>\n<meta property=\"og:site_name\" content=\"D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire\" \/>\n<meta property=\"article:modified_time\" content=\"2016-10-12T19:45:15+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/biochimie.umontreal.ca\/wp-content\/uploads\/sites\/37\/2012\/06\/Gerry2015-150x150.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/\",\"url\":\"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/\",\"name\":\"Gerardo Ferbeyre - D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire\",\"isPartOf\":{\"@id\":\"https:\/\/biochimie.umontreal.ca\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/biochimie.umontreal.ca\/wp-content\/uploads\/sites\/37\/2012\/06\/Gerry2015-150x150.jpg\",\"datePublished\":\"2012-06-26T14:51:18+00:00\",\"dateModified\":\"2016-10-12T19:45:15+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/#primaryimage\",\"url\":\"https:\/\/biochimie.umontreal.ca\/wp-content\/uploads\/sites\/37\/2012\/06\/Gerry2015-150x150.jpg\",\"contentUrl\":\"https:\/\/biochimie.umontreal.ca\/wp-content\/uploads\/sites\/37\/2012\/06\/Gerry2015-150x150.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/biochimie.umontreal.ca\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Department\",\"item\":\"https:\/\/biochimie.umontreal.ca\/en\/department\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Gerardo Ferbeyre\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/biochimie.umontreal.ca\/#website\",\"url\":\"https:\/\/biochimie.umontreal.ca\/\",\"name\":\"D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/biochimie.umontreal.ca\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Gerardo Ferbeyre - D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/","og_locale":"en_US","og_type":"article","og_title":"Gerardo Ferbeyre - D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire","og_description":"Professor Contact information D\u00e9partement de biochimie Facult\u00e9 de M\u00e9decine Universit\u00e9 de Montr\u00e9al Pavillon Roger-Gaudry, room E-515 C.P. 6128, Succ. Centre-ville Montr\u00e9al (Qu\u00e9bec) H3C 3J7 . P 514 343-7571 F 514 […]","og_url":"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/","og_site_name":"D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire","article_modified_time":"2016-10-12T19:45:15+00:00","og_image":[{"url":"https:\/\/biochimie.umontreal.ca\/wp-content\/uploads\/sites\/37\/2012\/06\/Gerry2015-150x150.jpg","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/","url":"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/","name":"Gerardo Ferbeyre - D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire","isPartOf":{"@id":"https:\/\/biochimie.umontreal.ca\/#website"},"primaryImageOfPage":{"@id":"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/#primaryimage"},"image":{"@id":"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/#primaryimage"},"thumbnailUrl":"https:\/\/biochimie.umontreal.ca\/wp-content\/uploads\/sites\/37\/2012\/06\/Gerry2015-150x150.jpg","datePublished":"2012-06-26T14:51:18+00:00","dateModified":"2016-10-12T19:45:15+00:00","breadcrumb":{"@id":"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/#primaryimage","url":"https:\/\/biochimie.umontreal.ca\/wp-content\/uploads\/sites\/37\/2012\/06\/Gerry2015-150x150.jpg","contentUrl":"https:\/\/biochimie.umontreal.ca\/wp-content\/uploads\/sites\/37\/2012\/06\/Gerry2015-150x150.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/biochimie.umontreal.ca\/en\/department\/gerardo-ferbeyre\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/biochimie.umontreal.ca\/en\/"},{"@type":"ListItem","position":2,"name":"Department","item":"https:\/\/biochimie.umontreal.ca\/en\/department\/"},{"@type":"ListItem","position":3,"name":"Gerardo Ferbeyre"}]},{"@type":"WebSite","@id":"https:\/\/biochimie.umontreal.ca\/#website","url":"https:\/\/biochimie.umontreal.ca\/","name":"D\u00e9partement de biochimie et m\u00e9decine mol\u00e9culaire","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/biochimie.umontreal.ca\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/biochimie.umontreal.ca\/en\/wp-json\/wp\/v2\/pages\/1116","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biochimie.umontreal.ca\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/biochimie.umontreal.ca\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/biochimie.umontreal.ca\/en\/wp-json\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/biochimie.umontreal.ca\/en\/wp-json\/wp\/v2\/comments?post=1116"}],"version-history":[{"count":7,"href":"https:\/\/biochimie.umontreal.ca\/en\/wp-json\/wp\/v2\/pages\/1116\/revisions"}],"predecessor-version":[{"id":13557,"href":"https:\/\/biochimie.umontreal.ca\/en\/wp-json\/wp\/v2\/pages\/1116\/revisions\/13557"}],"up":[{"embeddable":true,"href":"https:\/\/biochimie.umontreal.ca\/en\/wp-json\/wp\/v2\/pages\/11439"}],"wp:attachment":[{"href":"https:\/\/biochimie.umontreal.ca\/en\/wp-json\/wp\/v2\/media?parent=1116"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}